Pilot Study of Auto-immune Abnormalities Associated With Down Syndrome

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01041469

Acronym

IMMUTRI

Enrollment

Registered

2009-12-31

Start date

2009-11-30

Completion date

2010-12-31

Last updated

2012-03-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Down Syndrome With and Without Auto Immune Abnormalities

Keywords

Down syndrome, Humans,Clinical study,Immunity, Autoimmunity,

Brief summary

The purpose of the study is to identify biological data linked to auto immune abnormalities associated with Down Syndrome.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

8 Years to 36 Years

Healthy volunteers

Inclusion criteria

* Free and complete trisomy 21 * aged between 8 and 36 years * biological or clinical signs of auto-immune disorder (group 1) * no sign of auto-immune disorder (group 2)

Exclusion criteria

* any antimitotic or immune depressing treatment during the last 6 months * Current infectious disease * Corticosteroid therapy in the last 3 weeks * pregnancy

Design outcomes

Primary

Measure	Time frame
Auto-antibodies dosage	at enrolment
specific lymphocytes populations count	at enrolment

Countries

France

Outcome results