Botulinum Toxin Injection Efficiency

Effectiveness of Botulinum Toxin Injection After Exercising Splenius Capitis Muscle in Patients With Cervical Dystonia

Status

UNKNOWN

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01041157

Enrollment

Registered

2009-12-31

Start date

2008-09-30

Completion date

2011-12-31

Last updated

2009-12-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle Spasticity, Torticollis

Keywords

Torticollis, Botulinum Toxins

Brief summary

The purpose of the study is to examine the effect of the botulinum toxin injection into muscle tone, strength and mobility with and without muscle exercise effect.

Detailed description

The purpose is also to find out patients subjective symptoms between injections. Hypothesis: Efficiency of the botulinum toxin is more powerful with the muscle exercise before injection.

Interventions

OTHERResistance training

Neck muscle trainings effect on botulinum toxin efficiency

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

TRIPLE (Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Clinical diagnosis of cervical dystonia * Spasticity in splenius capitis muscle * Regular treatment with botulinum toxin injection

Exclusion criteria

* Don't want to take part the Trial * Very long distance from home to Jyväskylä Central Hospital

Design outcomes

Primary

Measure	Time frame
Muscle tone in splenius capitis muscle	five months

Secondary

Measure	Time frame
Pain in the neck	five months
Mobility in the neck	five months
Neck muscle strength	five months

Countries

Finland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026