Attention Deficit Hyperactivity Disorder
Conditions
Brief summary
The aim of the study is to assess the effect of Methylphenidate on cognitive performance and decision-making ability of ADHD adults, and to compare this effect to the effect on healthy control adults.
Detailed description
Two matched groups of adults - with and without ADHD diagnosis - will perform a battery of computerized tasks assessing sustained attention,working-memory,non-verbal IQ,and decision-making ability. In each group,half of the participants will perform the tasks after receiving a capsule containing methylphenidate (MPH), and the other half will perform the tasks after receiving placebo. Task performance measures will then be compared in order to assess the effect of MPH on these domains.
Interventions
DRUGmethylphenidate
a single doses of 10-20 mg in each one of two visits
DIETARY_SUPPLEMENTsweetener pill
a capsule containing a sweetener pill
Sponsors
Shalvata Mental Health Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
21 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* adults in the age of 21-50
Exclusion criteria
* pregnant or nursing women. * people who suffer from a psychiatric disorder other than ADHD which could account for their inattention symptoms better than ADHD. * people who lack judgment or are unable to communicate with the experimenters. * people who are incapable of performing the computerized tasks due to sensory or motor disabilities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| score in decision-making task 1 | by the end of the task |
Secondary
| Measure | Time frame |
|---|---|
| working memory task score | by the end of the task |
Countries
Israel
Outcome results
None listed