Clinically Severe Obesity
Conditions
Keywords
severe obesity, morbid obesity, gastric bypass, efficacy of gastric bypass
Brief summary
The main aim of this study is to analyze and report the very long-term outcomes after primary laparoscopic proximal Roux-en-Y gastric bypass surgery for clinically severe obesity.
Detailed description
There is lack of very-long term outcomes after bariatric surgery; A few series have been reported. However, most of them analyze medium-term outcomes. For RYGB, there are just two retrospective cohort studies reporting very long-term outcomes. Both studies have an open approach and a proximal Roux-en-Y configuration with different pouch orientation and size. MacLean´s series, with a better follow-up rate (83.4%), had a 67.6%EWL at a mean of 11.4 years; Failure rates were 20 and 35% for the morbidly obese and super obese, respectively. We will analyze our own series with a laparoscopic approach, vertically, lesser-curve base \< 10-15ml pouch and proximal Roux limb. The main end-points for our study are 1) Morbidity including status of specific biochemical markers & Mortality, 2) Weight loss expressed as BMI or %EWL, 3) Trends in major comorbidities and 4) Assessment of Quality of Life.
Interventions
None listed
Sponsors
University of California, San Francisco
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* patients who met NIH criteria for recommendation of a bariatric procedure with a combination of the following characteristics * status post primary laparoscopic proximal RYGB surgery with or without subsequent open or laparoscopic revisions or re-operations * follow up \> 10.0 years (Very long term outcome)
Exclusion criteria
* patients who had a previous gastric or bariatric procedure * patients who underwent primary laparoscopic RYGB somewhere else by other surgical group * missing records and/or unreachable patients with scant information for analysis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Morbidity and mortality | throughout follow-up |
| Weight loss expressed as Body Mass Index and Percentage excess weight loss | throughout follow-up |
| Comorbidity status | throughout follow-up |
| Health-related Quality of Life (HR-QoL) | at last follow-up |
| Subjective satisfaction | at the last follow-up |
Secondary
| Measure | Time frame |
|---|---|
| Nutritional and metabolic status | throughout follow-up |
Countries
United States
Outcome results
None listed