Osteoarthritis of Hip
Conditions
Brief summary
Orthopedic surgery is reportedly among the most painful surgical procedures. Surgical damage following major orthopedic surgery often involves a large, deep incision with considerable tissue dissection and muscle, bone, and vascular exposure. Post-operative pain after such surgery is exacerbated on movement or by reflex spasms of the muscles, which may delay mobilization, reduce satisfaction, prolong hospitalization, and possibly increase medical costs. We design a prospective randomized study for postoperative pain control following total hip arthroplasty.
Interventions
DRUGBupivacaine
DRUGPlacebo
Sponsors
Chang Gung Memorial Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* diagnosed for surgery of osteoarthritis of hip * ability to tolerate surgery under general anesthesia.
Exclusion criteria
* refusal or the lack of mental ability to provide informed consent * neuropathic pain or sensory disorders in the leg requiring surgery * previous surgery of the hip joint * coagulation abnormalities * severe renal or hepatic impairment * chronic opioid users * known history of intolerance to the drugs used in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain VAS score | pre-operaton, immediately post operation, postop 6hrs, postop 12hrs, postop 18hrs, postop 24hrs, post op 48hrs, postop 72hrs |
Secondary
| Measure | Time frame |
|---|---|
| Functional score: WOMAC hip score, SF-36 | Pre-operation, immediately post-operation, postop 6 weeks, postop 12 weeks |
Countries
Taiwan
Contacts
Primary ContactDave W. Chen, M.D.
Outcome results
None listed