A Study to Assess the Impact of Pneumococcal Conjugate Vaccination Programme on the Carriage of Pneumococci

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01040143

Acronym

Pneucast

Enrollment

450

Registered

2009-12-29

Start date

2008-01-31

Completion date

2010-03-31

Last updated

2019-03-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumococcal Disease

Keywords

Pneumococci, Streptococcus pneumoniae

Brief summary

A study taking swabs from the back of the nose (nasopharynx) to look at carriage of pneumococci.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

1 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Born in a cohort eligible for routine or catch up pneumococcal conjugate vaccination (i.e. date of birth since 4th September 2004) or a family member where a child is eligible and has been enrolled * Written informed consent given by the subject's parent/ legal guardian as well as assent from the child after the nature of the study has been explained to them or * Written informed consent given by the subject after the nature of the study has been explained to them

Exclusion criteria

* Moderate to severe disability. * Cerebral palsy, syndromes and neurological disorders affecting swallowing. * Ear Nose and Throat disorders affecting the anatomy of the ear,i.e.malformed ears. * Confirmed or suspected immunodeficiency (congenital or acquired). * On immunosuppressive therapy.

Design outcomes

Primary

Measure	Time frame
Presence of pneumococci in nasopharyngeal swabs	—

Countries

United Kingdom

Outcome results