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Epstein-Barr Detection in Oral Cancer

Epstein-Barr Detection in Squamous Cell Carcinoma and Healthy Oral Mucosa

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01039272
Enrollment
60
Registered
2009-12-24
Start date
2008-03-31
Completion date
2015-06-30
Last updated
2015-06-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Cancer

Keywords

oral cancer, EBV, PCR

Brief summary

The aim of this study is to analyze oral squamous cell carcinoma and healthy oral mucosa for the possible presence of Epstein-Barr virus (EBV).

Detailed description

Epstein-Barr virus has been implicated in a range of malignant neoplasms, including in some studies, in the aetiology of oral squamous cell carcinoma but the influence of EBV in oral cancer remains unclear. This study will examine the prevalence of EBV infection in oral cancer by means of nested polymerase chain reaction.

Interventions

None listed

Sponsors

UPECLIN HC FM Botucatu Unesp
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
40 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* patients of Oral Cancer Centre - UNESP/Araçatuba - SP * with oral squamous cell carcinoma

Exclusion criteria

* without oral squamous cell carcinoma

Design outcomes

Primary

MeasureTime frameDescription
presence of EBV1 hourEpstein-Barr virus has been implicated in a range of malignant neoplasms, including in some studies, in the aetiology of oral squamous cell carcinoma but the influence of EBV in oral cancer remains unclear. This study will examine the prevalence of EBV infection in oral cancer by means of nested polymerase chain reaction.

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026