Allergy, Asthma, Cardiovascular Disease, Osteoporosis, Type 2 Diabetes
Conditions
Keywords
epidemiology, risk factors, micronutrients
Brief summary
The overall aim of the Health2010-14 is to monitor the prevalence and trends of common chronic diseases (osteoporosis, diabetes, cardiovascular disease, asthma, allergy, and eczema) that are often un-diagnosed in the general population as well as biomarkers of micronutrient status. Specific aims include identification of novel lifestyle and genetic risk factors for the above diseases by investigating gene-lifestyle interactions.
Detailed description
Over a 5-year period a series of population-based studies are carried out including a total of up to 10,000 persons aged 18-69 years selected from the general population of Copenhagen, Denmark. The study also include a follow-up of a previous population study (the Health2006). Participants complete questionnaires on health, lifestyle, and social factors and undergo a health examination including measurements of metabolic biomarkers, allergy tests, anthropometric measures, bioimpedance, biomarkers of micronutrients, spirometry.
Interventions
None listed
Sponsors
Steno Diabetes Centre, Gentofte, Denmark
Glostrup University Hospital, Copenhagen
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 72 Years
Healthy volunteers
No
Inclusion criteria
* persons living in 10 municipalities of Copenhagen
Exclusion criteria
* pregnancy, non-Danish citizenship
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 5-year change in prevalence of biomarkers of chronic diseases (e.g. diabetes, asthma, allergy) and micronutrient status (e.g. vitamin D status). | 5 years |
Secondary
| Measure | Time frame |
|---|---|
| significant interaction (on a additive scale) between Vitamin D status and genetic variants in the Vitamin D receptor in relation to selected chronic disease biomarkers | 5 years |
Outcome results
None listed