Breast Cancer
Conditions
Keywords
BRCA mutation, benign breast disease, family history of breast cancer, strong family history of breast cancer, atypical ductal hyperplasia, atypical lobular hyperplasia, high risk for breast cancer
Brief summary
The purpose of this study is to increase understanding of women who are at high risk for developing breast cancer. Data from this group will be collected and entered into a registry. This registry serves as a clinical database to support research in prevention, early detection and treatment of breast cancer.
Detailed description
This is a longitudinal cohort study that collects data of eligible women at risk for developing breast cancer. Patient information will be entered into a secured computerized database that is used for research on the prevention, early detection and treatment of breast cancer.
Interventions
None listed
Sponsors
Women At Risk
New York Presbyterian Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* one or more first-degree relatives (mother, daughter, or sister) with pre-menopausal breast cancer * two or more first-degree relatives with post-menopausal breast cancer * tested positive for a BRCA1 or BRCA2 mutation * a history of biopsy-proven atypical ductal hyperplasia or atypical lobular hyperplasia * a history of biopsy-proven lobular neoplasia (lobular carcinoma in situ)
Exclusion criteria
* DCIS (ductal carcinoma in situ) * previous diagnosis of breast cancer
Countries
United States
Contacts
Primary ContactAmy C Whiffen, MPH
Backup ContactLisa Held, BA
Outcome results
None listed