Protein Hydrolyzation and Glycemic Control

The Additional Effects of Protein Hydrolysate Supplementation on Glucose Homeostasis in Type 2 Diabetes

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01034618

Enrollment

Unknown

Registered

2009-12-17

Start date

2007-12-31

Completion date

2009-04-30

Last updated

2009-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes

Keywords

Diabetes, protein, protein hydrolysate

Brief summary

The insulinotropic effects of protein hydrolysate/amino acid ingestion have been shown to regulate blood glucose homeostasis in both type 2 diabetes patients and normoglycemic controls. The objective of the study is to investigate the optimal dose of such an insulinotropic mixture.

Interventions

DIETARY_SUPPLEMENTProtein hydrolyzation

Study design

Intervention model

CROSSOVER

Primary purpose

BASIC_SCIENCE

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

MALE

Age

40 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Male * Age between 40 and 70 years * Oral blood glucose lowering medication * BMI \< 35 kg/m2

Exclusion criteria

* Exogenous insulin use * Cardiac disease (any cardiac event in the last 5 years) * Diabetic complications (microvascular complications, microalbuminuria: albumin:creatinine ratio \>2,5)

Design outcomes

Primary

Measure	Time frame
Glucose and insulin homeostasis.	—

Secondary

Measure	Time frame
Plasma amino acid profiles	—

Countries

Netherlands

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026