Effect of Feeding Frequency on Glucose and Insulin Metabolism and Substrate Partitioning

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01034293

Enrollment

Registered

2009-12-17

Start date

2009-10-31

Completion date

2010-06-30

Last updated

2010-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glucose Metabolism, Insulin

Keywords

feeding frequency, insulin metabolism, glucose metabolism, substrate partitioning

Brief summary

The purpose of this study is to determine the effect of feeding frequency on glucose and insulin metabolism and substrate partitioning.

Interventions

DIETARY_SUPPLEMENTlow feeding frequency (3x)

3 meals a day

DIETARY_SUPPLEMENTHigh feeding frequency (14x)

14 meals a day

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

MALE

Age

18 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* BMI: 18.5-25 kg/m2 (lean) * Gender: Male * Age: subjects has to be older than 18 and including 35 years old * Caucasian

Exclusion criteria

* Metabolic abnormalities such as: 1. Lactose intolerant 2. Diabetes Mellitus 3. Hypertension 4. Hypotension 5. Cardiovascular diseases 6. Asthma and other obstructive pulmonary diseases 7. Elevated fasting blood glucose level

Design outcomes

Primary

Measure	Time frame
Glucose and insulin metabolism	24 h

Secondary

Measure	Time frame
Substrate partitioning and metabolic markers	24 h

Countries

Netherlands

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 26, 2026