Optimal Treatment of Miscarriage

Which is the Optimal Treatment for Miscarriage With a Gestational ac in the Uterus and Which Factors Can Predict if the Treatment Will be Successful?

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01033903

Enrollment

190

Registered

2009-12-17

Start date

2008-10-01

Completion date

2018-03-01

Last updated

2018-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abortion, Spontaneous

Keywords

Abortion, Spontaneous, Randomized Controlled Trial

Brief summary

The main objective of the study is to determine if there is a difference in the number of women with a complete miscarriage after 10 days between expectant management versus treatment with 800 micrograms of misoprostol intravaginally in women with an an incomplete miscarriage before 14 weeks and a gestational sac retained in the uterus.

Interventions

DRUGmisoprostol

800 micrograms intravaginally ONCE

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* nonviable intrauterine pregnancy with retained gestational sac in the uterus * the embryo if visible 5 to 35 mm without a heart beat * vaginal bleeding * circulatory stable * hemoglobin at least 80 g/L

Exclusion criteria

* contraindications against misoprostol

Design outcomes

Primary

Measure	Time frame
complete miscarriage	10 days

Secondary

Measure	Time frame
complete miscarriage	17 days, 24 days, 31 days

Countries

Sweden

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 26, 2026