Substance Use Disorders
Conditions
Brief summary
1. Primary objective #1: Determine the relative effectiveness of MI-IOP and MI-PC in the full study sample with regard to treatment engagement over weeks 1-12 and cocaine/alcohol use over weeks 1-24. * Hypothesis 1: An intervention that explores several possible treatment options with the patient and provides the chosen option (e.g., MI-PC) will produce higher rates of treatment engagement than an intervention focused on engagement in IOP only (e.g., MI-IOP). * Hypothesis 2: An intervention that explores several possible treatment options with the patient and provides the chosen option (e.g., MI-PC) will produce better cocaine/alcohol use outcomes than an intervention focused on engagement in IOP only (MI-IOP). * Secondary analysis 1: Among the Non-engaged patients, determine rates of selection of each of the three options in MI-PC, retention rates within each option, and cocaine/alcohol use outcomes in each option. * Secondary analysis 2: Among the Engaged patients, determine rates of selection of each of the three options in MI-PC, retention rates within each option, and cocaine/alcohol use outcomes in each option. 2. Primary objective #2: Determine whether the relative effectiveness of MI-IOP and MI-PC varies as a function of engagement group, with regard to treatment engagement over weeks 1-12 and cocaine/alcohol use outcomes over weeks 1-24. * Hypothesis 1: The predicted main effect on retention favoring MI-PC over MI-IOP will be significantly larger among patients in the Non-engaged group than among those in the Engaged group. * Hypothesis 2: The predicted main effect on cocaine/alcohol use outcomes favoring MI-PC over MI-IOP will be significantly larger among patients in the Non-engaged group than among those in the Engaged group.
Detailed description
3\. Secondary objective #1: Examine outcomes on three secondary measures: percent days abstinent from all substances, negative consequences of drug use, and HIV high risk behaviors. * Hypothesis 1: Outcomes on the secondary measures will be better in MI-PC than in MI-IOP. 4\. Secondary objective #2: Test hypotheses concerning potential mediators of the predicted main effect favoring MI-PC over MI-IOP. * Hypothesis 1: The predicted advantage of MI-PC over MI-IOP will be mediated by greater increases in motivation, self-efficacy, commitment to abstinence, and self-help involvement in MI-PC. 5\. Secondary objective #3: Test hypotheses concerning effect of additional MI intervention after initial non-engagement persists through 12 weeks. * Hypothesis 1: A second telephone MI intervention will produce higher rates of subsequent engagement and less cocaine use than no further MI.
Interventions
BEHAVIORALMotivational Interviewing
2 sessions at week 2, potential 2 sessions at week 8 if the participant drops out.
BEHAVIORALTelephone counseling
one telephone counseling session per week for 10 weeks.
BEHAVIORALCognitive Behavioral Therapy (CBT) Counseling
One CBT session per week, for 10 weeks.
Prescription for naltrexone
BEHAVIORALIntensive OutPatient Therapy
Return to IOP, group therapy 3 times weekly for about three hours a day.
Sponsors
University of Pennsylvania
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
1. meet DSM-IV criteria for lifetime cocaine or alcohol dependence and have used cocaine or alcohol in the prior 6 months; 2. be \> 18 years of age; 3. be judged clinically appropriate for IOP (e.g., no current psychotic disorder or evidence of severe dementia, and no acute medical problem requiring inpatient treatment; 4. have no regular IV heroin use during the past year; 5. have access to a telephone; 6. be willing to be randomized and participate in research; and 7. no current participation in methadone or other forms of DA treatment, other than IOP. Finally, because of study follow-up requirements, subjects will 8. be required to be metropolitan area residents, and 9. be able to provide the name, verified telephone number, and address of at least two contacts who can provide locator information on the patient during follow-up. We will include patients with dependence on other substances, provided that they are cocaine dependent and meet other inclusion criteria.
Exclusion criteria
1. have a current psychotic disorder (as assessed with the psychotic screen from the MINI) or evidence of dementia severe enough to prevent participation in outpatient treatment; 2. have acute medical problem requiring immediate inpatient treatment; or 3. are currently participating in methadone or other forms of DA treatment, other than IOP.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Treatment Engagement | weeks 3 - 12 | Number of treatment sessions attended |
| Treatment Engagement for Participants Engaged at 2 Weeks, But Disengage Before 8 Weeks | weeks 9 - 12 | Number of treatment sessions attended |
| Treatment Engagement of Those Non-engaged at 2 Weeks and at 8 Weeks | weeks 9 - 12 | Number of treatment sessions attended |
| Any Drinking Days in Previous Month | Month 2 (weeks 5 - 8 post baseline) | Days of any drinking in previous month, as reported on Time Line Follow Back. This is a dichotomous measure, so the means that are reported are the percentage of people who have had any days of drinking during the follow up period specified. In other words, 0.57 indicates that 57% of the sample drank in the follow up period. |
| Any Drinking | Month 4 (weeks 13 - 15 post baseline) | Any drinking at follow up, as reported on Time Line Follow Back. This is a dichotomous measure, so the means that are reported are the percentage of people who have had any days of drinking during the follow up period specified. In other words, 0.57 indicates that 57% of the sample drank in the follow up period. |
| Percent Days Drinking | Month 2 (weeks 5 - 8 post baseline) | Percent days of any drinking at follow up, from Time Line Follow Back |
| Any Heavy Drinking Days | Month 2 (weeks 5 - 8 post baseline) | days of five or more drinks per drinking day for men, four or more drinks per drinking day for women, at follow up, from Time Line Follow Back. This is a dichotomous measure, so the means that are reported are the percentage of people who have had any days of heavy drinking during the follow up period specified. In other words, 0.57 indicates that 57% of the sample engaged in heavy drinking in the follow up period. |
| Percent Days Heavy Drinking | Month 2 (weeks 5 - 8 post baseline) | Percent days heavy drinking at follow up, from Time Line Follow Back \*heavy drinking is defined as five or more drinks per day for men, four or more for women |
| Any Cocaine Use | Month 3 (weeks 9 - 12 post baseline) | Any cocaine using self report, binary measure of percent days cocaine use. |
| Percent Days Cocaine Use | Month 3 (weeks 9 - 12 post baseline) | Percent days of any cocaine use, self reported |
Countries
United States
Participant flow
Pre-assignment details
All participants were enrolled when they entered IOP treatment. We collected baseline measures and monitored their treatment attendance. At 2 weeks, we determined whether they were engaged or nonengaged and randomized all participants at that time. Only those that were nonengaged at week 2 and still nonengaged at week 8 were rerandomized at week 8.
Participants by arm
| Arm | Count |
|---|---|
| Engaged Participants began treatment in IOP, consistently remained engaged in IOP throughout the study time period. This group did not reach the threshold of needing study intervention. | 227 |
| MI-PC Non-Engaged Participants began treatment in IOP but were not engaged at week 2. Randomized to receive patient choice.
Motivational Interviewing: 2 sessions at week 2, potential 2 sessions at week 8 if the participant drops out.
Telephone counseling: one telephone counseling session per week for 10 weeks.
Cognitive Behavioral Therapy (CBT) Counseling: One CBT session per week, for 10 weeks.
medication management: Prescription for naltrexone
Intensive OutPatient Therapy: Return to IOP, group therapy 3 times weekly for about three hours a day. | 93 |
| MI-IOP Non-Engaged Participants began treatment in IOP but were not engaged at week 2. Randomized back to IOP.
Motivational Interviewing: 2 sessions at week 2, potential 2 sessions at week 8 if the participant drops out. | 96 |
| MI-PC Engaged at 2 Weeks, Non-engaged Before 8 Weeks Participants began treatment in IOP and were engaged at week 2. However, they dropped out of treatment between weeks 3 - 8. Randomized to Patient Choice.
Motivational Interviewing: 2 sessions at week 2.
Telephone counseling: one telephone counseling session per week for 10 weeks.
Cognitive Behavioral Therapy (CBT) Counseling: One CBT session per week, for 10 weeks.
medication management: Prescription for naltrexone
Intensive OutPatient Therapy: Return to IOP, group therapy 3 times weekly for about three hours a day. | 41 |
| MI-IOP Engaged at 2 Weeks, Non-engaged Before 8 Weeks Participants began treatment in IOP and were engaged at week 2. However, they dropped out of treatment between weeks 3 - 8. Randomized back to IOP.
Motivational Interviewing: 2 sessions at week 2. | 43 |
| Total | 500 |
Baseline characteristics
| Characteristic | MI-PC Non-Engaged | MI-IOP Non-Engaged | MI-PC Engaged at 2 Weeks, Non-engaged Before 8 Weeks | Engaged | MI-IOP Engaged at 2 Weeks, Non-engaged Before 8 Weeks | Total |
|---|---|---|---|---|---|---|
| Age, Categorical <=18 years | 0 Participants | 0 Participants | 0 Participants | 0 Participants | 0 Participants | 0 Participants |
| Age, Categorical >=65 years | 2 Participants | 2 Participants | 0 Participants | 3 Participants | 0 Participants | 7 Participants |
| Age, Categorical Between 18 and 65 years | 91 Participants | 94 Participants | 41 Participants | 224 Participants | 43 Participants | 493 Participants |
| Age, Continuous | 48.02 years STANDARD_DEVIATION 9.84 | 47.7 years STANDARD_DEVIATION 9.38 | 47.8 years STANDARD_DEVIATION 9.42 | 49.4 years STANDARD_DEVIATION 8.35 | 48.5 years STANDARD_DEVIATION 9.64 | 48.29 years STANDARD_DEVIATION 8.92 |
| Region of Enrollment United States | 93 participants | 96 participants | 41 participants | 227 participants | 43 participants | 500 participants |
| Sex: Female, Male Female | 21 Participants | 21 Participants | 8 Participants | 36 Participants | 9 Participants | 95 Participants |
| Sex: Female, Male Male | 72 Participants | 75 Participants | 33 Participants | 191 Participants | 34 Participants | 405 Participants |
Adverse events
| Event type | EG000 affected / at risk | EG001 affected / at risk | EG002 affected / at risk | EG003 affected / at risk | EG004 affected / at risk |
|---|---|---|---|---|---|
| deaths Total, all-cause mortality | 0 / 227 | 0 / 93 | 0 / 96 | 1 / 41 | 0 / 43 |
| other Total, other adverse events | 0 / 227 | 0 / 93 | 0 / 96 | 0 / 41 | 0 / 43 |
| serious Total, serious adverse events | 34 / 227 | 16 / 93 | 9 / 96 | 4 / 41 | 4 / 43 |
Outcome results
Primary
Any Cocaine Use
Any cocaine using self report, binary measure of percent days cocaine use
Time frame: Month 4 (weeks 13 - 16 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Any Cocaine Use | 0.43 proportion of participants | Standard Deviation 0.5 |
| MI-IOP Non-Engaged at 2 Weeks | Any Cocaine Use | 0.29 proportion of participants | Standard Deviation 0.46 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Cocaine Use | 0.39 proportion of participants | Standard Deviation 0.5 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Cocaine Use | 0.23 proportion of participants | Standard Deviation 0.43 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Any Cocaine Use | 0.63 proportion of participants | Standard Deviation 0.49 |
| No Further Intervention | Any Cocaine Use | 0.45 proportion of participants | Standard Deviation 0.51 |
Primary
Any Cocaine Use
Any cocaine using self report, binary measure of percent days cocaine use
Time frame: Month 6 (weeks 21 - 24 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Any Cocaine Use | 0.35 proportion of participants | Standard Deviation 0.48 |
| MI-IOP Non-Engaged at 2 Weeks | Any Cocaine Use | 0.49 proportion of participants | Standard Deviation 0.5 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Cocaine Use | 0.35 proportion of participants | Standard Deviation 0.49 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Cocaine Use | 0.30 proportion of participants | Standard Deviation 0.47 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Any Cocaine Use | 0.54 proportion of participants | Standard Deviation 0.51 |
| No Further Intervention | Any Cocaine Use | 0.58 proportion of participants | Standard Deviation 0.5 |
Comparison: The statistical analyses used data from all follow up assessments.p-value: 0.1395% CI: [0.38, 1.14]Chi-squared
Comparison: The statistical analyses used data from all follow up assessments.p-value: 0.7195% CI: [0.33, 2.12]Chi-squared
Comparison: The statistical analyses used data from all follow up assessments.p-value: 0.3695% CI: [0.64, 3.4]Chi-squared
Primary
Any Cocaine Use
Any cocaine using self report, binary measure of percent days cocaine use
Time frame: Month 5 (weeks 17 - 20 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Any Cocaine Use | 0.45 proportion of participants | Standard Deviation 0.5 |
| MI-IOP Non-Engaged at 2 Weeks | Any Cocaine Use | 0.35 proportion of participants | Standard Deviation 0.48 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Cocaine Use | 0.35 proportion of participants | Standard Deviation 0.49 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Cocaine Use | 0.23 proportion of participants | Standard Deviation 0.43 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Any Cocaine Use | 0.58 proportion of participants | Standard Deviation 0.5 |
| No Further Intervention | Any Cocaine Use | 0.42 proportion of participants | Standard Deviation 0.5 |
Primary
Any Cocaine Use
Any cocaine using self report, binary measure of percent days cocaine use.
Time frame: Month 3 (weeks 9 - 12 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Any Cocaine Use | 0.45 proportion of participants | Standard Deviation 0.5 |
| MI-IOP Non-Engaged at 2 Weeks | Any Cocaine Use | 0.42 proportion of participants | Standard Deviation 0.5 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Cocaine Use | 0.31 proportion of participants | Standard Deviation 0.47 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Cocaine Use | 0.36 proportion of participants | Standard Deviation 0.49 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Any Cocaine Use | 0.66 proportion of participants | Standard Deviation 0.48 |
| No Further Intervention | Any Cocaine Use | 0.46 proportion of participants | Standard Deviation 0.51 |
Primary
Any Drinking
Any drinking at follow up, as reported on Time Line Follow Back. This is a dichotomous measure, so the means that are reported are the percentage of people who have had any days of drinking during the follow up period specified. In other words, 0.57 indicates that 57% of the sample drank in the follow up period.
Time frame: Month 6 (weeks 21 - 24 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Any Drinking | 0.56 proportion of participants | Standard Deviation 0.5 |
| MI-IOP Non-Engaged at 2 Weeks | Any Drinking | 0.31 proportion of participants | Standard Deviation 0.47 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Drinking | 0.50 proportion of participants | Standard Deviation 0.51 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Drinking | 0.27 proportion of participants | Standard Deviation 0.45 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Any Drinking | 0.42 proportion of participants | Standard Deviation 0.5 |
| No Further Intervention | Any Drinking | 0.63 proportion of participants | Standard Deviation 0.49 |
Comparison: The statistical analyses used data from all follow up assessments.p-value: 0.000795% CI: [0.23, 0.68]Chi-squared
Comparison: The statistical analyses used data from all follow up assessments.p-value: 0.1695% CI: [0.23, 1.27]Chi-squared
Comparison: The statistical analyses used data from all follow up assessments.p-value: 0.7995% CI: [0.48, 2.6]Chi-squared
Primary
Any Drinking
Any drinking at follow up, as reported on Time Line Follow Back. This is a dichotomous measure, so the means that are reported are the percentage of people who have had any days of drinking during the follow up period specified. In other words, 0.57 indicates that 57% of the sample drank in the follow up period.
Time frame: Month 4 (weeks 13 - 15 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Any Drinking | 0.49 proportion of participants | Standard Deviation 0.5 |
| MI-IOP Non-Engaged at 2 Weeks | Any Drinking | 0.26 proportion of participants | Standard Deviation 0.44 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Drinking | 0.42 proportion of participants | Standard Deviation 0.5 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Drinking | 0.30 proportion of participants | Standard Deviation 0.47 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Any Drinking | 0.50 proportion of participants | Standard Deviation 0.51 |
| No Further Intervention | Any Drinking | 0.47 proportion of participants | Standard Deviation 0.51 |
Primary
Any Drinking
Any drinking at follow up, as reported on Time Line Follow Back, This is a dichotomous measure, so the means that are reported are the percentage of people who have had any days of drinking during the follow up period specified. In other words, 0.57 indicates that 57% of the sample drank in the follow up period.
Time frame: Month 5 (weeks 16 - 20 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Any Drinking | 0.51 proportion of participants | Standard Deviation 0.5 |
| MI-IOP Non-Engaged at 2 Weeks | Any Drinking | 0.31 proportion of participants | Standard Deviation 0.47 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Drinking | 0.42 proportion of participants | Standard Deviation 0.5 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Drinking | 0.30 proportion of participants | Standard Deviation 0.47 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Any Drinking | 0.42 proportion of participants | Standard Deviation 0.5 |
| No Further Intervention | Any Drinking | 0.57 proportion of participants | Standard Deviation 0.5 |
Primary
Any Drinking Days in Previous Month
Any drinking days during previous month, as reported on Time Line Follow Back. This is a dichotomous measure, so the means that are reported are the percentage of people who have had any days of drinking during the follow up period specified. In other words, 0.57 indicates that 57% of the sample drank in the follow up period.
Time frame: Month 3 (weeks 9 - 12 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Any Drinking Days in Previous Month | 0.58 proportion of participants | Standard Deviation 0.5 |
| MI-IOP Non-Engaged at 2 Weeks | Any Drinking Days in Previous Month | 0.37 proportion of participants | Standard Deviation 0.49 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Drinking Days in Previous Month | 0.57 proportion of participants | Standard Deviation 0.5 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Drinking Days in Previous Month | 0.42 proportion of participants | Standard Deviation 0.5 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Any Drinking Days in Previous Month | 0.72 proportion of participants | Standard Deviation 0.45 |
| No Further Intervention | Any Drinking Days in Previous Month | 0.50 proportion of participants | Standard Deviation 0.51 |
Primary
Any Drinking Days in Previous Month
Days of any drinking in previous month, as reported on Time Line Follow Back. This is a dichotomous measure, so the means that are reported are the percentage of people who have had any days of drinking during the follow up period specified. In other words, 0.57 indicates that 57% of the sample drank in the follow up period.
Time frame: Month 2 (weeks 5 - 8 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Any Drinking Days in Previous Month | 0.57 proportion of participants | Standard Deviation 0.5 |
| MI-IOP Non-Engaged at 2 Weeks | Any Drinking Days in Previous Month | 0.37 proportion of participants | Standard Deviation 0.49 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Drinking Days in Previous Month | 0.46 proportion of participants | Standard Deviation 0.51 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Drinking Days in Previous Month | 0.41 proportion of participants | Standard Deviation 0.5 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Any Drinking Days in Previous Month | 0.60 proportion of participants | Standard Deviation 0.5 |
| No Further Intervention | Any Drinking Days in Previous Month | 0.63 proportion of participants | Standard Deviation 0.49 |
Primary
Any Heavy Drinking Days
five or more drinks per drinking day for men, four or more drinks per drinking day for women, at follow up, from Time Line Follow Back. This is a dichotomous measure, so the means that are reported are the percentage of people who have had any days of heavy drinking during the follow up period specified. In other words, 0.57 indicates that 57% of the sample engaged in heavy drinking in the follow up period.
Time frame: Month 3 (weeks 9 - 12 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Any Heavy Drinking Days | 0.44 proportion of participants | Standard Deviation 0.5 |
| MI-IOP Non-Engaged at 2 Weeks | Any Heavy Drinking Days | 0.26 proportion of participants | Standard Deviation 0.44 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Heavy Drinking Days | 0.36 proportion of participants | Standard Deviation 0.49 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Heavy Drinking Days | 0.33 proportion of participants | Standard Deviation 0.48 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Any Heavy Drinking Days | 0.55 proportion of participants | Standard Deviation 0.51 |
| No Further Intervention | Any Heavy Drinking Days | 0.32 proportion of participants | Standard Deviation 0.47 |
Primary
Any Heavy Drinking Days
days of five or more drinks per drinking day for men, four or more drinks per drinking day for women, at follow up, from Time Line Follow Back. This is a dichotomous measure, so the means that are reported are the percentage of people who have had any days of heavy drinking during the follow up period specified. In other words, 0.57 indicates that 57% of the sample engaged in heavy drinking in the follow up period.
Time frame: Month 2 (weeks 5 - 8 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Any Heavy Drinking Days | 0.49 proportion of participants | Standard Deviation 0.5 |
| MI-IOP Non-Engaged at 2 Weeks | Any Heavy Drinking Days | 0.24 proportion of participants | Standard Deviation 0.43 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Heavy Drinking Days | 0.36 proportion of participants | Standard Deviation 0.49 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Heavy Drinking Days | 0.24 proportion of participants | Standard Deviation 0.43 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Any Heavy Drinking Days | 0.47 proportion of participants | Standard Deviation 0.51 |
| No Further Intervention | Any Heavy Drinking Days | 0.34 proportion of participants | Standard Deviation 0.48 |
Primary
Any Heavy Drinking Days
five or more drinks per drinking day for men, four or more drinks per drinking day for women at follow up, from Time Line Follow Back. This is a dichotomous measure, so the means that are reported are the percentage of people who have had any days of heavy drinking during the follow up period specified. In other words, 0.57 indicates that 57% of the sample engaged in heavy drinking in the follow up period.
Time frame: Month 4 (weeks 13 - 16 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Any Heavy Drinking Days | 0.37 proportion of participants | Standard Deviation 0.49 |
| MI-IOP Non-Engaged at 2 Weeks | Any Heavy Drinking Days | 0.15 proportion of participants | Standard Deviation 0.36 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Heavy Drinking Days | 0.38 proportion of participants | Standard Deviation 0.49 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Heavy Drinking Days | 0.24 proportion of participants | Standard Deviation 0.44 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Any Heavy Drinking Days | 0.38 proportion of participants | Standard Deviation 0.49 |
| No Further Intervention | Any Heavy Drinking Days | 0.27 proportion of participants | Standard Deviation 0.45 |
Primary
Any Heavy Drinking Days
five or more drinks per day for men, four or more drinks per day for women, from Time Line Follow Back. This is a dichotomous measure, so the means that are reported are the percentage of people who have had any days of heavy drinking during the follow up period specified. In other words, 0.57 indicates that 57% of the sample engaged in heavy drinking in the follow up period.
Time frame: Month 5 (weeks 17 to 20 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Any Heavy Drinking Days | 0.37 proportion of participants | Standard Deviation 0.49 |
| MI-IOP Non-Engaged at 2 Weeks | Any Heavy Drinking Days | 0.19 proportion of participants | Standard Deviation 0.39 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Heavy Drinking Days | 0.38 proportion of participants | Standard Deviation 0.49 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Heavy Drinking Days | 0.24 proportion of participants | Standard Deviation 0.44 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Any Heavy Drinking Days | 0.25 proportion of participants | Standard Deviation 0.44 |
| No Further Intervention | Any Heavy Drinking Days | 0.33 proportion of participants | Standard Deviation 0.48 |
Primary
Any Heavy Drinking Days
five or more drinks per day for men, four or more drinks per day for women, from Time Line Follow Back. This is a dichotomous measure, so the means that are reported are the percentage of people who have had any days of heavy drinking during the follow up period specified. In other words, 0.57 indicates that 57% of the sample engaged in heavy drinking in the follow up period.
Time frame: Month 6 (weeks 21 - 24 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Any Heavy Drinking Days | 0.43 proportion of participants | Standard Deviation 0.5 |
| MI-IOP Non-Engaged at 2 Weeks | Any Heavy Drinking Days | 0.17 proportion of participants | Standard Deviation 0.38 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Heavy Drinking Days | 0.38 proportion of participants | Standard Deviation 0.49 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Any Heavy Drinking Days | 0.21 proportion of participants | Standard Deviation 0.42 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Any Heavy Drinking Days | 0.25 proportion of participants | Standard Deviation 0.44 |
| No Further Intervention | Any Heavy Drinking Days | 0.37 proportion of participants | Standard Deviation 0.49 |
Comparison: The statistical analyses used data from all follow up assessments.p-value: 0.000195% CI: [0.19, 0.58]Chi-squared
Comparison: The statistical analyses used data from all follow up assessments.p-value: 0.3695% CI: [0.29, 1.54]Chi-squared
Comparison: The statistical analyses used data from all follow up assessments.p-value: 0.4595% CI: [0.58, 3.54]Chi-squared
Primary
Percent Days Cocaine Use
Percent days of any cocaine use, self reported
Time frame: Month 6 (weeks 21 - 24 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Percent Days Cocaine Use | 7.76 percentage of days | Standard Deviation 16 |
| MI-IOP Non-Engaged at 2 Weeks | Percent Days Cocaine Use | 9.50 percentage of days | Standard Deviation 24.27 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Cocaine Use | 10.09 percentage of days | Standard Deviation 22.4 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Cocaine Use | 4.95 percentage of days | Standard Deviation 13.19 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Percent Days Cocaine Use | 15.57 percentage of days | Standard Deviation 28.02 |
| No Further Intervention | Percent Days Cocaine Use | 13.35 percentage of days | Standard Deviation 26.1 |
Comparison: The statistical analyses used data from all follow up assessments.p-value: 0.7595% CI: [-0.94, 0.6]Chi-squared
Comparison: The statistical analyses used data from all follow up assessments.p-value: 0.1695% CI: [-1.98, 0.3]Chi-squared
Comparison: The statistical analyses used data from all follow up assessments.p-value: 0.4295% CI: [-0.85, 2.04]Chi-squared
Primary
Percent Days Cocaine Use
Percent days of any cocaine use, self reported
Time frame: Month 3 (weeks 9 - 12 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Percent Days Cocaine Use | 12.61 percentage of days | Standard Deviation 25.38 |
| MI-IOP Non-Engaged at 2 Weeks | Percent Days Cocaine Use | 9.35 percentage of days | Standard Deviation 20.19 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Cocaine Use | 11.68 percentage of days | Standard Deviation 25.33 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Cocaine Use | 3.90 percentage of days | Standard Deviation 7.54 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Percent Days Cocaine Use | 18.45 percentage of days | Standard Deviation 28.68 |
| No Further Intervention | Percent Days Cocaine Use | 12.35 percentage of days | Standard Deviation 23.39 |
Primary
Percent Days Cocaine Use
Percent days of any cocaine use, self reported
Time frame: Month 5 (weeks 17 - 20 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Percent Days Cocaine Use | 10.87 percentage of days | Standard Deviation 23.78 |
| MI-IOP Non-Engaged at 2 Weeks | Percent Days Cocaine Use | 12.60 percentage of days | Standard Deviation 28.4 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Cocaine Use | 14.60 percentage of days | Standard Deviation 27 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Cocaine Use | 4.26 percentage of days | Standard Deviation 17.99 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Percent Days Cocaine Use | 19.14 percentage of days | Standard Deviation 33.07 |
| No Further Intervention | Percent Days Cocaine Use | 15.26 percentage of days | Standard Deviation 28.28 |
Primary
Percent Days Drinking
Percent days of any drinking at follow up, from Time Line Follow Back
Time frame: Month 6 (weeks 21 - 24)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Percent Days Drinking | 14.75 percentage of days | Standard Deviation 26.05 |
| MI-IOP Non-Engaged at 2 Weeks | Percent Days Drinking | 5.66 percentage of days | Standard Deviation 16.61 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Drinking | 19.05 percentage of days | Standard Deviation 34.19 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Drinking | 8.77 percentage of days | Standard Deviation 24.42 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Percent Days Drinking | 8.70 percentage of days | Standard Deviation 21.67 |
| No Further Intervention | Percent Days Drinking | 15.38 percentage of days | Standard Deviation 23.06 |
Comparison: The statistical analyses used data from all follow up assessments.p-value: 0.00995% CI: [-1.87, -0.29]Chi-squared
Comparison: The statistical analyses used data from all follow up assessments.p-value: 0.2395% CI: [-2.2, 0.52]Chi-squared
Comparison: The statistical analyses used data from all follow up assessments.p-value: 0.5895% CI: [-1.52, 0.85]Chi-squared
Primary
Percent Days Drinking
Percent days of any drinking at follow up, from Time Line Follow Back
Time frame: Month 2 (weeks 5 - 8 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Percent Days Drinking | 12.81 percentage of days | Standard Deviation 18.1 |
| MI-IOP Non-Engaged at 2 Weeks | Percent Days Drinking | 12.93 percentage of days | Standard Deviation 26.81 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Drinking | 17.35 percentage of days | Standard Deviation 29.12 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Drinking | 8.11 percentage of days | Standard Deviation 15.12 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Percent Days Drinking | 20.00 percentage of days | Standard Deviation 28.15 |
| No Further Intervention | Percent Days Drinking | 17.30 percentage of days | Standard Deviation 25.8 |
Primary
Percent Days Drinking
Percent days of any drinking at follow up, from Time Line Follow Back
Time frame: Month 3 (weeks 9 - 12 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Percent Days Drinking | 14.51 percentage of days | Standard Deviation 26.89 |
| MI-IOP Non-Engaged at 2 Weeks | Percent Days Drinking | 9.10 percentage of days | Standard Deviation 21.68 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Drinking | 15.31 percentage of days | Standard Deviation 25.49 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Drinking | 8.23 percentage of days | Standard Deviation 15.24 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Percent Days Drinking | 20.02 percentage of days | Standard Deviation 29.61 |
| No Further Intervention | Percent Days Drinking | 11.66 percentage of days | Standard Deviation 23.5 |
Primary
Percent Days Drinking
Percent days of any drinking at follow up, fromTime Line Follow Back
Time frame: Month 5 (weeks 17 - 20 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Percent Days Drinking | 18.37 percentage of days | Standard Deviation 29.86 |
| MI-IOP Non-Engaged at 2 Weeks | Percent Days Drinking | 8.22 percentage of days | Standard Deviation 19.78 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Drinking | 20.24 percentage of days | Standard Deviation 33.31 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Drinking | 11.47 percentage of days | Standard Deviation 28.57 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Percent Days Drinking | 6.99 percentage of days | Standard Deviation 15.09 |
| No Further Intervention | Percent Days Drinking | 20.60 percentage of days | Standard Deviation 27.9 |
Primary
Percent Days Drinking
Percent days of any drinking at follow up, from Time Line Follow Back
Time frame: Month 4 (weeks 13 - 16 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Percent Days Drinking | 15.76 percentage of days | Standard Deviation 26.16 |
| MI-IOP Non-Engaged at 2 Weeks | Percent Days Drinking | 8.96 percentage of days | Standard Deviation 24.65 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Drinking | 21.13 percentage of days | Standard Deviation 37.69 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Drinking | 13.42 percentage of days | Standard Deviation 29.38 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Percent Days Drinking | 6.37 percentage of days | Standard Deviation 11.55 |
| No Further Intervention | Percent Days Drinking | 18.81 percentage of days | Standard Deviation 31.37 |
Primary
Percent Days Heavy Drinking
Percent days heavy drinking at follow up, from Time Line Follow Back \* heavy drinking is defined as five or more drinks per drinking day for men, four or more for women
Time frame: Month 5 ( weeks 17 - 20 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Percent Days Heavy Drinking | 13.49 percentage of days | Standard Deviation 27.37 |
| MI-IOP Non-Engaged at 2 Weeks | Percent Days Heavy Drinking | 5.73 percentage of days | Standard Deviation 18.48 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Heavy Drinking | 20.09 percentage of days | Standard Deviation 33.4 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Heavy Drinking | 8.33 percentage of days | Standard Deviation 24.48 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Percent Days Heavy Drinking | 5.43 percentage of days | Standard Deviation 15.19 |
| No Further Intervention | Percent Days Heavy Drinking | 15.12 percentage of days | Standard Deviation 28.18 |
Primary
Percent Days Heavy Drinking
Percent days heavy drinking at follow up, from Time Line Follow Back \*heavy drinking is defined as five or more drinks per day for men, four or more for women
Time frame: Month 2 (weeks 5 - 8 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Percent Days Heavy Drinking | 11.73 percentage of days | Standard Deviation 18.28 |
| MI-IOP Non-Engaged at 2 Weeks | Percent Days Heavy Drinking | 7.14 percentage of days | Standard Deviation 20.11 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Heavy Drinking | 10.59 percentage of days | Standard Deviation 22.13 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Heavy Drinking | 6.37 percentage of days | Standard Deviation 14.85 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Percent Days Heavy Drinking | 12.98 percentage of days | Standard Deviation 22.48 |
| No Further Intervention | Percent Days Heavy Drinking | 10.49 percentage of days | Standard Deviation 21.16 |
Primary
Percent Days Heavy Drinking
Percent days heavy drinking at follow up, from Time Line Follow Back \* heavy drinking is defined as five or more drinks per day for men, four or more for women.
Time frame: Month 3 (weeks 9 - 12 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Percent Days Heavy Drinking | 10.58 percentage of days | Standard Deviation 22.61 |
| MI-IOP Non-Engaged at 2 Weeks | Percent Days Heavy Drinking | 6.05 percentage of days | Standard Deviation 17.92 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Heavy Drinking | 12.37 percentage of days | Standard Deviation 24.33 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Heavy Drinking | 5.65 percentage of days | Standard Deviation 14.09 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Percent Days Heavy Drinking | 14.16 percentage of days | Standard Deviation 24.53 |
| No Further Intervention | Percent Days Heavy Drinking | 3.99 percentage of days | Standard Deviation 9.04 |
Primary
Percent Days Heavy Drinking
Percent days heavy drinking at follow up, from Time Line Follow Back \*heavy drinking is defined as five or more drinks per drinking day for men, four or more for women
Time frame: Month 4 (weeks 13 - 16 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Percent Days Heavy Drinking | 11.56 percentage of days | Standard Deviation 23.55 |
| MI-IOP Non-Engaged at 2 Weeks | Percent Days Heavy Drinking | 7.01 percentage of days | Standard Deviation 23.15 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Heavy Drinking | 20.98 percentage of days | Standard Deviation 37.77 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Heavy Drinking | 8.98 percentage of days | Standard Deviation 24.84 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Percent Days Heavy Drinking | 5.75 percentage of days | Standard Deviation 11.73 |
| No Further Intervention | Percent Days Heavy Drinking | 13.93 percentage of days | Standard Deviation 30.18 |
Primary
Percent Days Heavy Drinking
Percent days heavy drinking at follow up, from Time Line Follow Back \*heavy drinking is defined as five or more drinks per drinking day for men, four or more for women
Time frame: Month 6 (weeks 21 - 24 post baseline)
Population: The number of participants analyzed represents the number that were available to provide research data. Those participants who were engaged and remained engaged in treatment were not included in these analyses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Percent Days Heavy Drinking | 11.30 percentage of days | Standard Deviation 23.91 |
| MI-IOP Non-Engaged at 2 Weeks | Percent Days Heavy Drinking | 3.77 percentage of days | Standard Deviation 15.34 |
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Heavy Drinking | 18.3 percentage of days | Standard Deviation 34.52 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Percent Days Heavy Drinking | 5.74 percentage of days | Standard Deviation 19.25 |
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Percent Days Heavy Drinking | 7.61 percentage of days | Standard Deviation 21.73 |
| No Further Intervention | Percent Days Heavy Drinking | 10.87 percentage of days | Standard Deviation 22.86 |
Comparison: The statistical analyses used data from all follow up assessments.p-value: 0.00395% CI: [-1.8, -0.39]Chi-squared
Comparison: The statistical analyses used data from all follow up assessments.p-value: 0.195% CI: [-1.1, 1.14]Chi-squared
Primary
Treatment Engagement
Number of treatment sessions attended
Time frame: weeks 3 - 12
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks | Treatment Engagement | 3.92 treatment days | Standard Deviation 3.27 |
| MI-IOP Non-Engaged at 2 Weeks | Treatment Engagement | 3.50 treatment days | Standard Deviation 3.23 |
p-value: 0.11Chi-squared
Primary
Treatment Engagement for Participants Engaged at 2 Weeks, But Disengage Before 8 Weeks
Number of treatment sessions attended
Time frame: weeks 9 - 12
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Engaged at 2 Weeks, Disengage Before 8 Weeks | Treatment Engagement for Participants Engaged at 2 Weeks, But Disengage Before 8 Weeks | 1.28 treatment days | Standard Deviation 1.55 |
| MI-IOP Engaged at 2 Weeks, Disengage Before 8 Weeks | Treatment Engagement for Participants Engaged at 2 Weeks, But Disengage Before 8 Weeks | 0.76 treatment days | Standard Deviation 1.25 |
p-value: 0.02Chi-squared
Primary
Treatment Engagement of Those Non-engaged at 2 Weeks and at 8 Weeks
Number of treatment sessions attended
Time frame: weeks 9 - 12
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| MI-PC Non-engaged at 2 Weeks, Still Non-engaged at 8 Weeks | Treatment Engagement of Those Non-engaged at 2 Weeks and at 8 Weeks | 0.58 treatment days | Standard Deviation 1.11 |
| No Further Intervention | Treatment Engagement of Those Non-engaged at 2 Weeks and at 8 Weeks | 0.30 treatment days | Standard Deviation 0.76 |
p-value: 0.005Chi-squared