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Chronic Alcohol and Brain Stress Circuit Response

Chronic Alcohol and Brain Stress Circuit Response

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01031264
Enrollment
120
Registered
2009-12-14
Start date
2009-01-31
Completion date
2014-12-31
Last updated
2015-07-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alcoholism, Stress

Keywords

social drinkers

Brief summary

Alcoholism is among the top three causes of preventable death and disease in the US (Mokdad et al., 2004; Room et al., 2005). Stress plays an important role in the development of alcoholism and in high vulnerability to alcohol relapse. This study will provide a greater understanding of the mechanism by which stress and alcohol consumption interacts to influence development of compulsive alcohol seeking and vulnerability to stress-induced drinking, and the results will have significant implications for the development of new prevention and treatment interventions for alcoholism.

Interventions

None listed

Sponsors

National Institute on Alcohol Abuse and Alcoholism (NIAAA)
CollaboratorNIH
Yale University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
21 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

* ages 21-50

Design outcomes

Primary

MeasureTime frameDescription
Assess differences in reactivity to cue imagery2 years from start of studyPhysiological measures will be collected (heart rate, blood levels), self-reports of emotional states completed & alcohol taste task performed

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026