Study of Atenolol Influence on Blood Pressure During Resistance Exercise

Blood Pressure Response During Resistance Exercise in Hypertensives: Influence of Beta-blockers

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01030016

Enrollment

Registered

2009-12-10

Start date

2007-05-31

Completion date

2009-05-31

Last updated

2009-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Pressure, Exercise

Keywords

resistance exercise, beta-blockers, blood pressure

Brief summary

The study was designed to investigate if atenolol is able to blunt blood pressure increase during resistance exercise in hypertensive subjects.

Detailed description

The study compared intra-arterial blood pressure responses during leg-extension resistance exercise performed to fatigue at 40, 80 and 100% of 1 RM in hypertensive patients receiving placebo (first) and atenolol (second) on a single blind manner.

Interventions

DRUGatenolol

25 mg/day, twice a day for 6 weeks

Study design

Allocation

NON_RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

SUPPORTIVE_CARE

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

30 Years to 60 Years

Healthy volunteers

Inclusion criteria

* hypertension with blood pressure levels below 160/105 mmHg under placebo. * age between 30 and 60 years * nonobese

Exclusion criteria

* target organ lesion * cardiovascular risk factor * cardiovascular disease * physically active

Design outcomes

Primary

Measure	Time frame
blood pressure during resistance exercise	6 weeks

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026