Evaluation of Metabolism-Boosting Beverages

The Effect of Metabolism-Boosting Beverages on 24 Hr Energy Expenditure

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01029236

Enrollment

Registered

2009-12-09

Start date

2007-06-30

Completion date

2007-12-31

Last updated

2009-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Appetite, Energy Expenditure

Keywords

obesity, metabolism, weight loss, energy expenditure, thermogenesis, Metabolism-Boosting Beverages effect on REE, Metabolism-Boosting Beverages effect on appetite

Brief summary

The purpose of this study is to assess the effect of Metabolism-boosting Beverages (MBB) containing green tea extract with a standardized amount of epigallocatechin gallate (EGCG) and caffeine.

Detailed description

The study will assess the effect of MBB's on 24 hour energy expenditure by performing indirect calorimetry, and on appetite using visual analogue scales (VAS). The planned sample size is 54 healthy male and female adults, both lean and overweight. We plan to test 6 metabolism-boosting beverages in the following order: 1) Raspberry Tea 2) Banana Shake 3) Chai Latte 4) Strawberry Shake 5) Cappuccino 6) Hot Cocoa. In the order that they are screened, each subject will be assigned to receive 1 of 6 Metabolism-boosting beverages. Each MBB will contain 90 mg EGCG and 100 mg caffeine.

Interventions

OTHERMedifast Metabolism-boosting Beverages

Medifast metabolism-boosting beverages containing 90 mg EGCG and 100 mg caffeine.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Adult males and females (age between 18 and 65) * BMI ≥18.5 - ≤ 40.0 kg/m2 * Non-smokers * No known food allergies to wheat, gluten, soy or nuts * ≤ 14 alcoholic beverages per week * No sensitivity to caffeine or green tea * No alcohol or caffeine on days when metabolism is tested * Willing and able to give informed consent * Not currently using appetite-affecting medications (e.g SSRIs, steroids, Ritalin) * Not pregnant or lactating

Exclusion criteria

* Actively dieting * Chronic uncontrolled health problems (not including obesity or controlled: type-2 diabetes, hyperlipidemia, hypertension) * History of arrhythmia, or taking anti-arrhythmic medications (e.g. propafenone) * Schizophrenia, history of bipolar disorder, current Major Depressive Disorder * Dependence on alcohol or sedative-hypnotic drugs (e.g. benzodiazepines) * Cognitive impairment severe enough to preclude informed consent * Taking weight loss or appetite-suppressant medications * Taking appetite affecting medications (e.g. SSRIs, steroids, Ritalin) * Food allergies to wheat, gluten, soy, or nuts * Sensitivity to caffeine or green tea

Design outcomes

Primary

Measure	Time frame
To assess the effect of MBBs on REE by performing indirect calorimetry	30, 60, 90, and 120 minutes

Secondary

Measure	Time frame
To assess the effect of MBBs on appetite via visual analogue scales	30, 60, 90, and 120 minutes

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026