Gastroesophageal Reflux Disease
Conditions
Keywords
laparoscopy, fundoplication, Nissen, Thal, children, operative treatment of gastro-oesophageal reflux disease in children
Brief summary
Laparoscopic fundoplication is increasingly performed in paediatric surgery. Many types of fundoplication are performed, each has advantages and disadvantages. The Nissen operation is the most frequently performed procedure in the U.K., however it can be associated with post-operative dysphagia. The relative benefits between Nissen and other fundoplication techniques in children are still uncertain. The aim of our study was to compare the long-term outcomes following laparoscopic Nissen fundoplication with laparoscopic Thal fundoplication in children.
Interventions
PROCEDURElaparoscopic Nissen/laparoscopic Thal
Sponsors
Oxford University Hospitals NHS Trust
Study design
Primary purpose
TREATMENT
Eligibility
Sex/Gender
ALL
Age
1 Months to 21 Years
Healthy volunteers
No
Inclusion criteria
* Gastro-oesophageal reflux unresponsive to medical treatment, or those who had serious complications (e.g. apnoea, aspiration pneumonia, oesophagitis)
Exclusion criteria
* Patients who had previous anti-reflux surgery, previous open abdominal surgery, if parents declined to participate into study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence of symptoms sufficiently severe to justify the need for additional revisional surgery (i.e. failure of the original surgery) | — |
| Early death following surgery directly related to the fundoplication technique | — |
Secondary
| Measure | Time frame |
|---|---|
| The resumption of symptoms bad enough to necessitate the re-introduction of anti-reflux medication (but not sufficiently bad to require revisional surgery) i.e. intention to treat | — |
| Post-operative complications (e.g. post-operative dysphagia) | — |
Countries
United Kingdom
Outcome results
None listed