Spinal Cord Injury
Conditions
Keywords
spinal cord injury, cardiovascular disease, dietary patterns
Brief summary
This study will look at dietary patterns in individuals with chronic spinal cord injuries and the relationship between these dietary patterns and cardiovascular disease risk factors. The study is a supplement to the Coronary Artery Risk Development in Young Adults (CARDIA) study. The dietary history from CARDIA will be used. The investigators' primary hypothesis is the following: Greater whole-grain and dietary fiber intake will be favorably associated with adiposity (BMI and WC) and metabolic CVD risk factors (fasting glucose, fasting insulin, HOMA-IR, diabetes, hsCRP, TC, HDL-C, triglycerides, TC/HDL-C ratio, non-HDL-C, and systolic and diastolic blood-pressure) among a sample of individuals with SCI aged 38-50 who have been injured \>1 year.
Detailed description
This study is a cross-sectional study. It will look at dietary patterns in individuals with chronic spinal cord injuries and the relationship between these dietary patterns and cardiovascular disease risk factors. The study is a supplement to the Coronary Artery Risk Development in Young Adults (CARDIA) study. The dietary history from CARDIA will be used. The investigators' primary hypothesis is the following: Greater whole-grain and dietary fiber intake will be favorably associated with adiposity (BMI and WC) and metabolic CVD risk factors (fasting glucose, fasting insulin, HOMA-IR, diabetes, hsCRP, TC, HDL-C, triglycerides, TC/HDL-C ratio, non-HDL-C, and systolic and diastolic blood-pressure) among a sample of individuals with SCI aged 38-50 who have been injured \>1 year.
Interventions
None listed
Sponsors
University of Minnesota
Wake Forest University Health Sciences
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
38 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* Male or female, black or white with SCI due to a nonvascular insult that caused an acute spinal cord injury (i.e. traumatic injury, transverse myelitis without a diagnosis of multiple sclerosis, surgical complication, or benign neoplasm) at least 1 year prior to enrollment including ASIA A,B,C * Age at time of enrollment: \> 38 years and \<55 years (i.e., on or after 38th birthday and before 55th birthday) * Voluntary, informed consent of participant * Participant willing to comply with the testing protocols and questionnaires * Communication and comprehension sufficient for compliance with all testing procedures and measures
Exclusion criteria
* SCI of a vascular or malignant etiology * Pregnancy, end-stage renal disease, treatment for cancer except for non-melanoma skin cancer in the past five years * Injury \< 1 years prior to enrollment * ASIA D * Chronic, nontobacco substance-abuse
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Whole-grain intake | Day - 30 | Average number of whole grain servings per day |
| Fruit and vegetable intake | Day - 30 | Average number of fruit and vegetable servings per day |
| Dairy intake | Day - 30 | Average number of dairy servings per day |
Secondary
| Measure | Time frame |
|---|---|
| LDL-C | Year 1 |
| Waist circumference | Year 1 |
| Triglycerides | Year 1 |
| Total cholesterol | Year 1 |
| HDL-C | Year 1 |
Countries
United States
Outcome results
None listed