Study of the Causes of the Breakdown of Muscle Fibers in Hospitalized Patients

Rhabdomyolysis - A Retrospective Study in Hospitalized Patients

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01022450

Enrollment

2500

Registered

2009-12-01

Start date

2009-11-30

Completion date

Unknown

Last updated

2009-12-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Renal Failure, Myopathy, Neuroleptic Malignant Syndrome, Rhabdomyolysis

Keywords

rhabdomyolysis, myopathy, acute renal failure, neuroleptic malignant syndrome, Pharmaceutical Preparations, Hydroxymethylglutaryl-CoA Reductase Inhibitors, fibrates, creatine kinase

Brief summary

1. Analyze the various causes of breakdown of muscle fibers in hospitalized patients. 2. Analyze the characteristics of these patients in Taiwan (including the drugs history, risk factors and the incidence of complications).

Detailed description

1. Find the causes of breakdown of muscle fibers in hospitalized patients through medical record review. * especially drug-related 2. Find the risk factors of muscle fibers breakdown.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Patients who admitted to The National Taiwan University Hospital during 2003/1/1\ 2008/12/31 with the following discharge diagnosis: myoglobinuria, rhabdomyolysis, myopathy, toxic myopathy, malignant hyperthermia, neuroleptic malignant syndrome, polymyositis, myalgia and had acute neuromuscular illness presentations and serum creatinine kinase (CK) more than 5 times the upper limit of normal (male \> 900 IU/L; female \> 835 IU/L).

Exclusion criteria

* Patients with recent myocardial infarction or stroke, unless clinical history, examination, or electromyography showed a concomitant myopathy.

Countries

Taiwan

Contacts

Primary ContactFe-Lin L Wu, MSCP, PhD

flwu@ntu.edu.tw+886-2-23123456

Backup ContactKwan-Dun Wu, MD, PhD

kdwu@ntuh.gov.tw+886-2-23123456

Outcome results