Preconditioning Volatile Anesthesia in Liver Surgery

Preconditioning is Indeed Protective

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01021228

Enrollment

257

Registered

2009-11-26

Start date

2008-08-31

Completion date

2009-10-31

Last updated

2009-11-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia

Keywords

Liver resection, Continuous volatile anesthesia, Continuous intravenous anesthesia, Preconditioning volatile anesthesia, Comparing three groups of anesthesia during the liver surgery according to their benefit on liver and outcome.

Brief summary

The purpose of this study is to compare the impact and outcome of continuous volatile anesthesia to continuous intravenous anesthesia and to preconditioning volatile anesthesia in liver surgery.

Detailed description

Comparing the impact and outcome of continuous volatile anesthesia to continuous intravenous anesthesia and to preconditioning volatile anesthesia in liver surgery.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

* \> 18 years * benign and malign disease * any type of liver surgery * inflow occlusion during the liver surgery

Exclusion criteria

* \< 18 years * participation on other interventional and treatment randomized controlled trials, * trauma of the liver * liver cirrhosis

Design outcomes

Primary

Measure	Time frame
peak ALT and AST levels representing the ischemia-reperfusion injury	post-operative

Secondary

Measure	Time frame
length of hospital stay, length of ICU stay, blood loss and morbidity (post-operative complications)	post-operative

Countries

Switzerland

Outcome results