Chronic Pelvic Pain
Conditions
Keywords
Chronic pelvic pain, ilioinguinal nerve entrapment, randomized study, Chronic pelvic pain in women
Brief summary
Neuralgic pain caused by entrapment of peripheral nerves is an often overlooked cause of chronic pelvic pain. The objective of the present study was to assess pain and quality of life in women with pain caused by entrapment of the ilioinguinal nerve, iatrogenic after surgery but also found without previous surgery. In a controlled prospective cross-over study 19 women were randomized either to medical treatment or to resection of the nerve. Statistically significant improvements were found after surgical resection.
Interventions
DRUGAmitryptiline, gabapentin
For amitryptiline starting dose 20-30 mg at night, increasing until clinical effect. For gabapentin was the initial dose 300 mg tid with rapid increases up to 800 mg tid.
PROCEDUREResection of the ilioinguinal nerve
In general anaesthesia the nerve was identified and resected as central as possible
Sponsors
Göteborg University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
15 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Pelvic pain in which a careful investigation has shown signs of ilioinguinal nerve entrapment
Exclusion criteria
* Drug abuse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvements in pain according to Visual Analogue Scales. Improvements in quality of life according to Psychological General Well-Being-scales. | At least one year after intervention,in some cases more then five years. |
Countries
Sweden
Outcome results
None listed