Effect of Mobilization on Acute Postoperative Pain and Nociceptive Function

Effect of Mobilization on Acute Postoperative Pain and Nociceptive Function After Total Knee Arthroplasty: A Prospective, Consecutive, Trial

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01018277

Enrollment

Registered

2009-11-23

Start date

2009-12-31

Completion date

2010-06-30

Last updated

2012-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain, Postoperative, Pain Sensitivity, Postoperative

Brief summary

Aim of the present study is twofold. * First we want to evaluate the effect of mobilization on acute postoperative pain * Second to test weather chances in pain sensitivity are occurring following surgery and mobilization after total knee arthroplasty

Detailed description

Little is known about the effect of mobilization on acute postoperative pain and mobilization induced pain, and if altered pain sensitivity occur under these circumstances. * First we want to evaluate the effect of mobilization on acute postoperative pain using the visual analog scale (VAS) * Second to test weather chances in pain sensitivity are occurring following surgery and mobilization after total knee arthroplasty, using two simple tools, the Pain Matcher and a Pressure Algometer.

Interventions

OTHERMobilization (walking)

25 meters twice

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients scheduled for total unilateral knee arthroplasty

Exclusion criteria

* Cognitive dysfunction or peripheral / central neurological dysfunction inconsistent with protocol completing * Alcohol and medical abuse (as defined by the National Health Service of Denmark * Daily use of opioids or glucocorticoids

Design outcomes

Primary

Measure	Time frame	Description
Pain score on the visual analog scale (difference before and after two mobilisation seances)	up to 24 hours	pain at rest (supine) 5 min after exercise(after the 2nd walk)

Secondary

Measure	Time frame	Description
Pain score on the visual analog scale (difference before and after two mobilisation seances)	up to 24 hours	pain at rest (supine) 20 min after the 2nd walk, pain during passive hip flexion and pain during passive knee flexion 5 and 20 min after the 2nd walk, as well as pain during the 2nd walk after 6 and 25 m
Pain sensitivity measured with pressure algometry and with pain matcher (difference before and after two mobilisation seances and difference before and after surgery)	up to 24 hours	Nociceptive function before and after postoperative exercise

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026