Alopecia Areata
Conditions
Brief summary
Conventional treatments include the use of steroids applied locally, or injection in to the legion, or oral therapy. Treatment is determined by the severity of the disease. Injection in to the legion can be done in two methods 1. Subcutaneous injection syringe Lower 2. Using syringe DERMOJET - a syringe without a needle. So far there are no publications in the medical literature of studies comparing efficacy, safety, convenience of use for doctor-patient, of both methods.
Interventions
DEVICESubcutaneous injection luer syringe
Right scalp: Luer syringe. Left scalp: syringe without a needle. All injections will contain 0.1 ml of Depo Medrol - Methylprednisolone acetate 40 mg/2 ml. The distance between injection locations will be 1 cm.
DEVICEDERMOJET (a syringe without a needle)
Right scalp: Luer syringe. Left scalp: syringe without a needle. All injections will contain 0.1 ml of Depo Medrol - Methylprednisolone acetate 40 mg/2 ml. The distance between injection locations will be 1 cm.
Sponsors
Sheba Medical Center
Study design
Intervention model
PARALLEL
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Subjects over the age of 18 2. Men and women 3. The presence of at least two lesions (centers) in diameter of at least 1.5 cm on both sides of the scalp. 4. Healthy with no diseases that constitute the background against the total label use steroids
Exclusion criteria
1. Pregnant women 2. Involvement of more then 50% of the scalp 3. Patients with immunodeficiency-related diseases 4. Patients receiving systemic steroids
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of lesions will be based on Global assessment of improvement, score of 0-5 | 1 year |
Secondary
| Measure | Time frame |
|---|---|
| Pain level will be evaluated based on a scale of 0-10 | 1 year |
Countries
Israel
Outcome results
None listed