Tibial Fracture
Conditions
Keywords
Pin-site infection, silversulfadiazine, open fracture, open tibial fracture underwent external fixator
Brief summary
This study aimed to compare the efficacy of pin-tract infection prevention between silversulfadiazine and dry dressing. Methods: 30 patients with an open tibial fracture admitted to Songklanagarind hospital from September 2007 to June 2008 and treated by emergency debridement and external fixation were randomized into two groups, one treated with silversulfadiazine for infection prophylaxis (15) and a control group treated with dry dressing only (15). All patients were followed until the external fixator was removed. Pin-site infections were assessed and graded at each follow-up visit by an orthopaedist blinded to the mode of treatment. A culture from the pin site was done if an infection occurred.
Interventions
DRUGsilversulfadiazine
apply once a day
Sponsors
Prince of Songkla University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
15 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Open tibial fracture treated with external fixator age between 15-60 years
Exclusion criteria
* Immunocompromised patients (diabetes, HIV or malignancy)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of pin site infection | 2 years |
Secondary
| Measure | Time frame |
|---|---|
| type of organism | 2 years |
| severity of pin site infection | 2 years |
Countries
Thailand
Outcome results
None listed