Effect of Turmeric on Diabetic Nephropathy

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01015937

Enrollment

Registered

2009-11-18

Start date

2008-03-31

Completion date

2009-08-31

Last updated

2009-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic Nephropathy, Proteinuria

Keywords

diabetes, nephropathy, turmeric, serum IL8, serum TGFb, serumINF, urinary IL8, urine TGFb

Brief summary

The purpose of this study is to investigate whether turmeric is effective in improvement of diabetic nephropathy and in decrease in the amount of proteinuria and cytokine levels.

Detailed description

Diabetic nephropathy is leading cause of ESRF that many therapy recommended for it. In this study, we investigate effect of turmeric on diabetic nephropathy, thus we selected diabetic nephropathy patients and divided them into 2 groups. One group received turmeric + ACE inhibitor + Angiotensin II receptor blocker (ARB) and the second group received only ACE inhibitor + ARB.

Interventions

DRUGTurmeric extract

turmeric 500 mg TID for 45 days

DRUGAngiotensin-converting enzyme (ACE) inhibitor + Angiotensin-II type 1 receptor (ATI) blocker

maximum dosage as patient tolerated for 45 days

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* diabetic nephropathy * more than 300 mg proteinuria/day * age more than 18 years old

Exclusion criteria

* DM type 1

Countries

Iran

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026