Basal Cell Carcinoma
Conditions
Keywords
basal cell carcinoma, photodynamic therapy, photo chemotherapy, basal cell epithelioma
Brief summary
The purpose of this study is to evaluate the efficacy of photodynamic therapy in treatment of Basal cell carcinoma (BCC) and factors that affect response rate.
Detailed description
Background and Aim: Basal cell carcinoma (BCC) is the most common skin cancer .Photodynamic therapy \_as a novel , non-invasive therapeutic approach \_may be considered a valuable strategy. This study was designed with the aim of the evaluation of efficacy of PDT in treatment of BCC and factors that may affect response rate. Materials and Methods: This was a clinical trial which was done on 28 BCCs. Patients were treated with ALA-PDT monthly for 1-6 sessions and evaluated for clinical response,cosmetic results and probable side effects.
Interventions
RADIATIONphotodynamic therapy
treatment of bcc with 5\_ALA cream 20% topical administration once monthly+ photodynamic therapy (red light) 120 j/cm2 once monthly
Sponsors
Shahid Beheshti University of Medical Sciences
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Histologically proven BCCs
Exclusion criteria
* Rodent ulcer * Morphea type * ANA + * History of photosensitivity or photodermatosis or ingestion of phototoxic * Drugs during last month * Pregnancy * Breast feeding * Age\< 18 * History of another therapeutic intervention for bcc during last 6 months
Outcome results
None listed