Study About the Effect of Doxycycline and Acetylcystein in the Treatment of CD-associated Fistulae

FIST-MC-09 Study About the Effect of Doxycycline and Acetylcystein in the Treatment of CD-associated Fistulae

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01012726

Enrollment

Registered

2009-11-13

Start date

2009-11-30

Completion date

2012-07-31

Last updated

2014-12-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Crohn's Disease

Brief summary

The investigators will study whether local instillation of Doxycycline and Acetylcystein results in fistula closure in CD patients.

Interventions

PROCEDUREColonoscopy

During the colonoscopy, we instill Acetylcystein and Doxycyline into the fistula.

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* fistulizing CD * CD \< 6 months * at least one insufficient fistula closure try

Exclusion criteria

* CDAI \> 200 * Abscesses * CRP \> 100

Design outcomes

Primary

Measure	Time frame
Fistula closure	01.08.2009 - 31.07.2012

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026