Red Cell Mass and Plasma Volume Measurements in Elderly Men and Women With Anemia

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01011361

Enrollment

Registered

2009-11-11

Start date

2009-04-30

Completion date

2011-06-30

Last updated

2016-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anemia

Brief summary

On the basis that the clinical consequences of seemingly trivial levels of anemia are surprisingly severe, this study investigates if hemoglobin concentration accurately represents the underlying red cell mass in elderly patients with unresolved anemia.

Detailed description

For the study, the routine clinical measurement of hemoglobin will be compared to true red cell mass and plasma volume in elderly patients with anemia.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

Inclusion criteria

* 65 and older * Anemia (hemoglobin \< 13 g/dL in men or \< 12 g/dL in women) * Outpatient at either the Stanford Health Care (SHC) Medical Center or VA Palo Alto Health Care System

Exclusion criteria

* Body mass index (BMI): * \< 18.5 kg/m2 * \> 35 kg/m2 * Palpable splenomegaly * Contraindication to RBC mass/plasma volume testing * On any experimental pharmacologic agent in the prior 2 months

Design outcomes

Primary

Measure	Time frame
Red blood cell mass	1 day

Secondary

Measure	Time frame
Plasma volume measurements	1 day

Countries

United States

Outcome results