Hodgkin Lymphoma
Conditions
Brief summary
The Gruppo Italiano Studio Linfomi has been collecting data on patients with Hodgkin Lymphoma (HL) since 1988. This archive represents a homogeneous series of consecutive patients with HL. The very long follow up and the availability of clinical and treatment data make it feasible to perform a study on the gonadal toxicity related to treatment for HL.
Interventions
None listed
Sponsors
Gruppo Italiano Studio Linfomi
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* Female patients in complete remission after chemotherapy for Hodgkin lymphoma * Age ≥ 18 e \< 40 years * Previous regular menstrual cycle * No previous or concomitant gynecological diseases affecting reproducing function * No other chemo-radiotherapy for other neoplasm * Written informed consent
Exclusion criteria
* none
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of gonadal toxicity in terms of irreversible amenorrhea and infertility, in women of reproductive age with Hodgkin lymphoma treated with chemotherapy. | from end of treatment until date of last contact/visit |
Secondary
| Measure | Time frame |
|---|---|
| role of a prophylactic treatment with oral contraceptives and GnRH analogs in preventing gonadal damage | from end of treatment until date of last contact/visit |
Countries
Italy
Contacts
Primary ContactAntonella Montanini, BSc, PhD
Outcome results
None listed