Cardiomyopathy, Chagas Disease, Exercise Training
Conditions
Keywords
Chagas Disease, Chagas Cardiomyopathy, Exercise Movement Techniques
Brief summary
The benefits of exercise training in heart failure are well established. Its effects, however, have not been evaluated in Chagas cardiomyopathy (ChC). The investigators hypothesis is that the exercise training may improve functional capacity, quality of life (QoL), and reduce brain natriuretic peptide (BNP) levels in patients with ChC.
Interventions
OTHERExercise training
Sponsors
Federal University of Minas Gerais
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
30 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Chronic Chagas dilated cardiomyopathy, defined by the echocardiography finding of a dilated left ventricle with moderate or severe impaired left ventricular systolic function (left ventricular ejection fraction ≤ 45%). * To be clinically stable for at least 3 months * To have sinus rhythm * To be under standard medical therapy use at the time.
Exclusion criteria
* Inability to attend regular exercise training * The presence of a pacemaker, associated cardiac or systemic diseases * Practitioners of regular physical activity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Functional capacity | 12 weeks |
| Functional class | 12 weeks |
| Health related quality of life | 12 weeks |
| BNP levels | 12 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Complications related to the exercise training | 12 weeks |
Countries
Brazil
Outcome results
None listed