Liver Cirrhosis
Conditions
Brief summary
Sleep disturbance and sexual dysfunction are common complaints of patients with cirrhosis . The term sleep disturbance describes insomnia, poor quality sleep, circadian rhythm disorders and obstructive sleep apnea and is associated with reduced health-related quality of life (HRQoL) score indices. Sleep and sexual disorders have only been formally evaluated in small studies in these patients and to date, no studies have objectively assessed these patients. In addition, no studies have been performed in these patients after liver transplantation. The investigators' hypothesis is that sleep and sexual disturbance is commonly seen in patients with advanced cirrhosis and improves after liver transplantation. However, despite this, HRQoL remain impaired because of residual sleep disturbance.This study will be unique in providing cross-sectional follow-up of patients with cirrhosis at baseline and after liver transplantation (\> 6 months).
Interventions
None listed
Sponsors
University Health Network, Toronto
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* Liver cirrhosis * Comprehend and read English * On liver transplantation list or post-liver transplantation
Exclusion criteria
* Non-English speaking * \< 18 years and \> 85 yrs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sleep disturbances in patients with advanced cirrhosis | 18 months |
Countries
Canada
Outcome results
None listed