Pancreatitis
Conditions
Keywords
erythromycin, prokinetics, nasojejunal tubes, Bengmark feeding tube, post-pyloric feeding, pancreatitis, Non-critically ill patients having pancreatitis who require jejunal enteral nutrition
Brief summary
The purpose of this study is to assess the effect of erythromycin on the Rate of Success in Placement of a Self-propelled Feeding Tube.
Interventions
DRUGErythromycin
Subjects receive 4x250mg erythromycin i.v. daily after intubation of a self-propelled feeding tube
DRUGPlacebo
Subjects receive 4x placebo i.v. daily after intubation of a self-propelled feeding tube
Sponsors
Canisius-Wilhelmina Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Aged 18-80 years * Having pancreatitis * Require jejunal enteral nutrition
Exclusion criteria
* Known impaired peristalsis (critically ill patients, postoperative patients, history of surgery of the stomach/duodenum) * Pregnancy * Hypersensibility to erythromycin * Cardiac arrhythmias with a prolonged QT-time * Simultaneous usage of drugs impairing peristalsis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The success rate of spontaneous positioning the tubes tip into the jejunum, beyond Treitz ligament, after 48 hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| The success rate of spontaneous positioning the tubes tip into the jejunum, beyond Treitz ligament, after 24 hours. | — |
| Adverse events using this self-propelled tube | — |
Outcome results
None listed