Major Depressive Disorder
Conditions
Keywords
Depression, Major Depression
Brief summary
The purpose of this study is to determine the usefulness of a stress reduction treatment in helping minority patients with major depression get better. Subjects will receive six weeks of either mindfulness-based stress reduction and problem solving therapy or psychoeducation.
Detailed description
The purpose of this study is to determine the usefulness of a stress reduction treatment compared to psychoeducation in helping minority patients with major depression get better. The study will last 10 weeks. During the main portion of the study, subjects will receive either individual weekly sessions of stress-reduction therapy or psychoeducation for six weeks. The stress reduction therapy will consist of mindfulness-based stress reduction and problem solving therapy, which focuses on linking psychological problems with psychosocial issues and helping you use your skills and resources to improve your functioning. The psychoeducation will consist of six sessions of education on depression and the treatment and management of symptoms. Each session will last 50 minutes, and four of the visits will also include filling out questionnaires which will take approximately 15-30 minutes to complete. One month after the last session, subjects will come in for a follow-up visit with a study clinician to see how they are doing and to fill out questionnaires.
Interventions
BEHAVIORALMindfulness Based Stress Reduction and Psychoeducation
Participants will receive six individual weekly 50-minute sessions of mindfulness based stress reduction (MBSR) as well as problem solving therapy (PST. PST is a type of therapy that focuses on psychosocial problems and using your skills and resources to function better. MBSR uses exercises in mindfulness to reduce stress.
BEHAVIORALPsychoeducation
Participants will receive six individual weekly 50-minute sessions of psychoeducation. Psychoeducation consists of education on depression, its symptoms, its treatment, and recovery.
Sponsors
Dupont-Warren
Trina E. Chang, MD
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Meet criteria for current major depressive disorder * Men or women aged 18-75 who self-identify as a member of a racial or ethnic minority group * Has a PCP, therapist, psychiatrist, etc aware of their depression. Or, subject agrees to seek outside mental health treatment/management
Exclusion criteria
* Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Feasibility (rate of enrollment, attrition) | 2 years |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Perceived stress | Week 10 | We will assess perceived stress at week 10 of subjects' study participation, although we allow for a 12-week period for subjects to complete the study. |
Countries
United States
Outcome results
None listed