Gestational Diabetes Mellitus and Cardiovascular Disease: The Role of Vascular Dysfunction

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00998712

Enrollment

Registered

2009-10-20

Start date

2009-08-31

Completion date

2014-01-31

Last updated

2013-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gestational Diabetes Mellitus, Pregnancy

Keywords

gestational diabetes mellitus, pregnancy, cardiovascular disease risk

Brief summary

The purpose of this research study is to look at whether there are differences in blood vessel function, risk for developing diabetes (high blood sugar), lipid (blood fat) levels, and levels of other blood markers between black women and white women who have or do not have gestational diabetes mellitus.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy women of self-identified African descent (black) and European (white) ancestry, * 18-40 years of age, * Body mass index \< 35 kg/m2 * History of regular menstrual cycles, * Are currently pregnant and in third trimester of pregnancy (after 24 weeks gestational age) * Have no pregnancy-associated complications to-date * Are in good health free of hypertension, as well as thyroid, cardiac, or renal disease.

Exclusion criteria

* History of smoking * Are taking potentially vasoactive medications

Design outcomes

Primary

Measure	Time frame
endothelial function	same day

Countries

United States

Contacts

Primary ContactResearch Assistant

RBLResearchGroup@partners.org617-724-3504

Backup ContactRhonda Bentley-Lewis, MD, MBA

rbentleylewis@partners.org617-726-2874

Outcome results