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Optimizing Resuscitation After Cardiac Arrest in the Community

Optimizing Resuscitation After Cardiac Arrest in the Community: Increasing the Probability of Survival While Reducing Costs

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00998140
Enrollment
1600
Registered
2009-10-20
Start date
2009-03-31
Completion date
2021-10-31
Last updated
2020-11-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiopulmonary Arrest Outcome

Keywords

resuscitation, sudden death, cardiopulmonary resuscitation, emergency medical services, termination of resuscitation, ventricular fibrillation, out-of-hospital cardiac arrest, asystole, medical futility, withdrawing treatment, transportation of patients, health expenditures, healthcare costs

Brief summary

Resuscitative efforts have been shown to be unsuccessful in most cases of out-of-hospital cardiac arrest (OHCA), and survivors who do recover cardiac function often sustain severe hypoxic brain damage. Time to efficacious care is a primary determinant of disability-free survival. In the Jerusalem district, only 9% of OHCA patients present with ventricular tachycardia/ventricular fibrillation (VT/VF) as the primary rhythm, whereas 77% present with asystole; this seems primarily to be the result of long collapse-to-arrival times. Nevertheless, overly zealous resuscitation is undertaken in a high proportion of arrests with a futile prognosis, leading to excessive costs. Study hypotheses: 1. Subpopulations for whom intervention is futile/counter-productive are identifiable 2. Substantial waste of resources can be avoided 3. Optimization of emergency medical services (EMS) reorganization without adding resources is an achievable goal

Interventions

None listed

Sponsors

Shaare Zedek Medical Center
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* All victims of non-traumatic out-of hospital cardiopulmonary arrest (defined as the absence of either spontaneous respiration or palpable pulse or both) within the Jerusalem district.

Exclusion criteria

* Patients with do-not-resuscitate orders or an advance directive to that effect.

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026