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Acute and Longlasting Side Effects Caused by Radiotherapy in the Head and Neck Area

Acute and Longlasting Side Effects Caused by Radiotherapy in the Head and Neck Area

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00995319
Enrollment
58
Registered
2009-10-15
Start date
2008-01-31
Completion date
2014-07-31
Last updated
2017-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and Neck Cancer

Keywords

mouth, Mucositis, Dysphagia, malnutrition, Xerostomia, saliva, tooth injuries

Brief summary

The purpose of this clinical investigation is to evaluate acute and longlasting side effects in patients undergoing radiotherapy for cancer treatment in the head and neck area.

Detailed description

The Dental Team at the Department for Oral and Maxillofacial Surgery in Trondheim takes care of patients before, during and also after radiotherapy in the head and neck area. In spite of the use of advanced radiation protocols and prevention measures such as fluoridation splints the team observes significant side effects, both under radiation and also on the long term after concluding treatment. Common problems are for example dermal and mucosal damages, reduced salivation, dysphagia and lesions of the teeth. Aim of the study is the investigation and documentation of side effects and complications in relation to the oral cavity. During the acute and postradiation phase a continuous follow-up over a longer lasting period is proceeded with registration of all relevant parameters. This includes among others dental status and evaluation of quality of life.

Interventions

None listed

Sponsors

St. Olavs Hospital
CollaboratorOTHER
Helse Midt-Norge
CollaboratorOTHER
Norwegian University of Science and Technology
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* radiation concerning the oral cavity * follow-up at the Dental Team

Exclusion criteria

* refused approval * survival prognosis under one year

Design outcomes

Primary

MeasureTime frame
salivary flow3 months

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026