Knee Osteoarthritis
Conditions
Keywords
Knee Osteoarthritis, Manual Therapy, Therapeutic Exercise, Ultrasound, Effusion
Brief summary
Earlier research has shown that exercising while receiving manual therapy improves function and reduces pain in people with knee osteoarthritis. However, very little is known about the mechanisms by which manual therapy and exercise reduce pain and improve function. This study will ask subjects with knee osteoarthritis to receive one of the following interventions: (1) no treatment, (2) exercise only, or (3) manual therapy only. Measures will be taken of the patient's knee range of motion, knee swelling and pain before and after receiving the intervention. These measures will be analyzed to determine what effect exercise and manual therapy applied to the knee have on improving knee range of motion and reducing knee pain and swelling. Swelling will be measured using an ultrasound device which is used to take pictures inside the knee. This type of ultrasound measurement is painless and harmless.
Interventions
PROCEDUREManual Therapy
Grade 1 and 2 oscillatory manual mobilization of the tibiofemoral joint at various ranges of motion.
BEHAVIORALTherapeutic Exercise
Subjects will perform 5 minutes of lower extremity cycle ergometer with minimal resistance followed by 10 minutes of resistance exercise to the quadriceps at 3 tibiofemoral positions (0 degrees, 30 degrees and 60 degrees of knee flexion).
BEHAVIORALVideo Observation
Subjects will watch a 15 minute video on a health topic unrelated to knee osteoarthritis.
Sponsors
Texas Tech University Health Sciences Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 89 Years
Healthy volunteers
Yes
Inclusion criteria
* Diagnosis of knee osteoarthritis.
Exclusion criteria
* Inability to ambulate at least 100 feet, ride a stationary bicycle for at least 10 minutes, or lie in the prone position for at least 10 minutes, * Intra-articular knee injection within one month of study inception, * A history of exercise induced or uncontrolled angina within three months of the study entry, * Severe dyspnea at rest, * Previous bilateral total knee arthroplasty, * Pregnancy, OR * The absence of knee pain at the time of recruitment for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Suprapatellar effusion measured via diagnostic ultrasound | Outcome measure will be measured 1 minute prior to intervention and 1 minute after intervention. |
Secondary
| Measure | Time frame |
|---|---|
| Pain Visual Analog Scale | Outcome measure will be measured 3 minutes prior to intervention and 3 minutes after intervention. |
| Goniometric knee arc range of motion | Outcome measure will be measured 5 minutes prior to intervention and 5 minutes after intervention. |
| Western Ontario and McMaster Universities Index of osteoarthritis of the knee | Outcome measure will be measured 12 minutes prior to intervention and 7 minutes after intervention. |
Countries
United States
Outcome results
None listed