Energy Expenditure Responses to Acute Exercise in Older Women (Calorie Expenditure and Exercise)

Energy Expenditure Responses to Acute Exercise in Older Women

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00988299

Acronym

CEE

Enrollment

Registered

2009-10-02

Start date

2009-10-31

Completion date

2011-12-31

Last updated

2011-12-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aging

Keywords

older, NEAT, exercise, RMR, energy expenditure

Brief summary

In older, normal-weight women (60-75 yrs, BMI=18-28 kg/m2), an acute bout of higher-intensity (60% of maximum effort) aerobic exercise, in comparison to an isocaloric bout of lower-intensity (45% of maximum effort) exercise (caloric expenditure of 3.5 kcal/kg body weight for both), will result in differential: 1. decline in non-exercise activity calorie expenditure in the subsequent 48 hours after exercise; 2. increase in resting metabolic rate 48 hours after exercise; 3. increase in serum free triiodo-L-thyronine (free T3) concentrations immediately following exercise; 4. decline from pre-exercise in plasma leptin and serum free T3 concentrations 48 hours after exercise.

Interventions

OTHERexercise

exercise sessions at 45% and 60% of maximum effort

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

60 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

1. Women 2. Age 60-75 years 3. normal weight 4. Weight-stable (± 5%) within the previous 3 months 5. Non-smoking for last year 6. Able to provide own transportation to study visits 7. Not currently involved in any other research study 8. Willing and able to participate in all aspects of the trial including research testing 9. Willing to give informed consent to participate

Exclusion criteria

1. Self-reported significant cardiovascular disease 2. Other self-reported medical conditions such as diabetes, chronic or recurrent respiratory conditions, active cancer, musculoskeletal disease 3. Medications known to affect exercise performance or metabolism 4. Excess caffeine use (\> 500mg/day) 5. Any self-reported contraindications to exercise 6. Clinical depression 7. Abnormal cognitive function -

Design outcomes

Primary

Measure	Time frame
non-exercise activity calorie expenditure	2 days after exercise sessions

Secondary

Measure	Time frame
resting metabolic rate	2 days after exercise sessions

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026