Opiate Dependence
Conditions
Keywords
opioid dependence, suboxone, HIV risk behavior
Brief summary
This study tests whether starting Suboxone (buprenorphine) during a medical hospitalization, and then providing an appointment (a link) for after discharge to maintenance buprenorphine in an outpatient setting will reduce HIV risk behavior in individuals who inject opioids.
Detailed description
In this randomized controlled trial, medically hospitalized opioid dependent patients will be assigned to a treatment as usual group, where they will receive a detox regiment of Suboxone during their hospital stay, or a linkage group, where they receive a maintenance course of Suboxone during their hospital stay, and appointment post-discharge with an outpatient Suboxone clinic/provider and a Suboxone prescription to use between discharge and this appointment. Study interviews are completed at baseline, and 1, 3- and 6-months post-baseline. Primary outcomes are opioid use and HIV risk behavior.
Interventions
BEHAVIORALLinkage
This intervention provides an outpatient appointment with a Suboxone provider for medically hospitalized opioid-dependent patients to attend post-discharge.
Sponsors
Boston Medical Center
Butler Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* 18 years of age or older * Current opioid injector, at least weekly in the past month * Current opioid dependence, SCID confirmed * Currently receiving an inpatient buprenorphine detoxification protocol.
Exclusion criteria
* Patients unable to be interviewed due to acute illness or cognitive impairment * In police custody, expecting incarceration * Persons who cannot provide two contact persons (including shelters, parole officers, etc.) to verify location * Not able to complete assessments in English * Enrolled in a methadone maintenance program * Plans to leave the area within the next 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| opioid use | baseline, 1-month, 3-months, 6-months |
| HIV risk behavior | baseline, 1-month, 3-months, 6-months |
Secondary
| Measure | Time frame |
|---|---|
| reduction in injection-related medical conditions | baseline, 1-month, 3-months, 6-months |
| reduction in emergency department and hospital utilization | baseline, 1-month, 3-months, 6-months |
Countries
United States
Outcome results
None listed