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Carpal Tunnel Syndrome: Case Reports and Analysis - Ultrasound Imaging and Pathomechanics of Median Nerve Compression

Carpal Tunnel Syndrome: Case Reports and Analysis - Ultrasound Imaging and Pathomechanics of Median Nerve Compression

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00987571
Enrollment
4
Registered
2009-10-01
Start date
2009-04-30
Completion date
2009-09-30
Last updated
2009-10-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carpal Tunnel Syndrome

Keywords

carpal tunnel syndrome, median nerve, ultrasound, electrodiagnosis, Normal subjects

Brief summary

Carpal tunnel syndrome is caused by compression of the median nerve at the wrist. The hypothesis is that ultrasound imaging can be used to visualize nerve compression in carpal tunnel patients during hand activity, and normal subjects will not demonstrate any nerve compression.

Detailed description

Two patients with carpal tunnel syndrome underwent nerve testing to document that they had median nerve abnormality at the wrist. They subsequently had ultrasound imaging of the wrist at rest and during a stress test using hand activity. Two control subjects had nerve testing to prove that they had no nerve abnormality at the carpal tunnel. The carpal tunnel syndrome patients demonstrated nerve compression on the ultrasound images during the stress tests and the normal subjects showed no nerve compression.

Interventions

None listed

Sponsors

EMG Labs of Arizona Arthritis & Rheumatology Associates
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
Yes

Inclusion criteria

* Patients must have symptoms consistent with carpal tunnel syndrome and electrodiagnostic testing that demonstrates abnormal median nerve function at the wrist, consistent with carpal tunnel syndrome. * Normal subjects must have no upper limb symptoms to support carpal tunnel syndrome and normal nerve testing.

Exclusion criteria

* Patients excluded if nerve testing was not consistent with carpal tunnel syndrome. * Normals excluded if nerve testing demonstrated any median nerve abnormality.

Design outcomes

Primary

MeasureTime frame
Median nerve compressive narrowing on ultrasound imaging in carpal tunnel syndrome patients5 months

Secondary

MeasureTime frame
No median nerve compressive narrowing in normal subjects5 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026