Bronchiolitis, Convulsion, Febrile, Gastroenteritis
Conditions
Keywords
acute bronchiolitis, acute gastroenteritis, febrile convulsion, viral agents, molecular methods
Brief summary
With the use of molecular methods new viruses have been detected in respiratory and gastrointestinal tracts of both patients and asymptomatic subjects in recent years. The clinical importance of these viruses has not been adequately studied. The aim of this study is to use molecular methods to detect viruses in upper respiratory tract and gastrointestinal tract of children with acute bronchiolitis, acute gastroenteritis and febrile convulsions and to try to correlate the severity of clinical picture with the amount of viruses present in clinical samples. The investigators will also try to detect the increase in specific antibodies in paired sera.
Interventions
None listed
Sponsors
University of Ljubljana School of Medicine, Slovenia
University Medical Centre Ljubljana
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 5 Years
Healthy volunteers
Yes
Inclusion criteria
presence of * acute bronchiolitis * acute gastroenteritis * febrile convulsion requiring hospital admission
Exclusion criteria
* none
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To describe the clinical picture of a viral respiratory and/or gastrointestinal infection associated with a specific viral pathogen | In a 14-day period |
Secondary
| Measure | Time frame |
|---|---|
| To correlate the severity of clinical picture with the quantity of virus in clinical samples | In a 14-day period |
Countries
Slovenia
Contacts
Primary ContactMarko Pokorn, MD, MSc
Backup ContactTatjana Mrvič, MD, MSc
Outcome results
None listed