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Spinal Cord Injury: Endurance, Strength and Cardiac Function Induced by Efficient Training Protocols

Spinal Cord Injury: Endurance, Strength and Cardiac Function Induced by Efficient Training Protocols

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00987155
Enrollment
12
Registered
2009-09-30
Start date
2007-01-31
Completion date
2012-05-31
Last updated
2017-01-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Disease

Keywords

Functional electrical stimulation cycling, arm crank, wheelchair, ergometry, paraplegia, spinal cord injury, exercise testing

Brief summary

1. Measurements of peak oxygen uptake (VO2peak) during passive leg cycling (PLC) combined with arm crank ergometry (ACE), leg vascular occlusion (100mmHg above systolic BP) combined with ACE, and FES isometric contractions combined with ACE in spinal cord injured (SCI). All the above mentioned parameters will be compared to Functional Electrical Stimulated (FES) lower extremity cycling combined with ACE (FEShybrid). The hypothesis is that VO2peak is significantly higher during FES hybrid cycling when compared to peak and submaximal PLC, leg vascular occlusion and ACE. But the values for VO2peak during FES isometric contractions combined with ACE is not significantly different from FES hybrid cycling. 2. Comparison of sub-maximal and peak VO2 values during arm crank (ACE) and wheelchair ergometry (WCE) in persons with spinal cord injury. The hypothesis is that wheelchair propulsion due to higher energy expenditure show higher work output and VO2peak than ACE. 3. Does 6 weeks of maximal strength training improve SCI subjects performance during WCE? WCE after 6 weeks maximal strength training is less strenuous owing to better work economy/ efficiency. 4. Effect from aerobic high intensity hybrid training on stroke volume (SV) and VO2peak in spinal cord injured men. 8 weeks of high intensity 4 times 4 interval training at 85-90% of peak heart rate during hybrid cycling. Hypothesis; VO2peak and SV will be significantly increased from training.

Interventions

DEVICEErgometry

MetamaxII Cortex ergospirometry system (Cortex Biophysik GmbH, Germany). Arm cycling ergometer (Ergomed 840L, Siemens, GermanyMonark, Sweden), Electrically braked wheelchair ergometer (VP 100, Handisoft France)

Sponsors

St. Olavs Hospital
CollaboratorOTHER
Norwegian University of Science and Technology
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes

Inclusion criteria

* Paraplegia, sensorimotor complete injury AIS A to motor complete, sensory incomplete AIS B. Chronic neurological state with stabile spontaneous recovery compared to baseline AIS. At least year since injury. * Be able to tolerate direct current stimulation in the means of FES * Living in Health region IV and V, Norway.

Exclusion criteria

* Pacemaker (demand type) * Known cancer * Known pregnancy * Severe autonomic dysreflexia * Gross contractures

Design outcomes

Primary

MeasureTime frame
Maximal oxygen uptake2 years

Secondary

MeasureTime frame
Blood lactate2 years
Blood Pressure2 years
Perceived Exertion2 years
Generated power (W)2 years

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 2, 2026