Type 2 Diabetes Mellitus
Conditions
Brief summary
The purpose of this study is to determine if daily supplementation with 2000 International Units of Vitamin D will improve hemoglobin A1c in uncontrolled type 2 diabetics.
Detailed description
Vitamin D is typically understood to support musculoskeletal health when administered concomitantly with calcium. A number of recent studies suggest, however, that this important nutrient may play a significant role in many pathophysiological processes, including diabetes mellitus. With the prevalence of diabetes mellitus ever increasing, novel mechanisms for controlling blood glucose and hemoglobin A1c are being sought to help prevent the costly and debilitating complications of this chronic disease.
Interventions
DIETARY_SUPPLEMENTVitamin D3 2000 international units daily
Vitamin D3 2000 international unit tablets once daily for 3 months
DIETARY_SUPPLEMENTVitamin C 500mg daily
Vitamin C 500mg tablets once daily for 3 months
Sponsors
ProMedica Health System
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
21 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Type 2 diabetes mellitus * Hemoglobin A1c \>7% measured in the 3 months prior to randomization * Age 21 to 75 years
Exclusion criteria
* Renal insufficiency (defined as CrCl \<30mL/min) * Gestational diabetes * Malabsorption syndrome * Patients taking vitamin D supplements at doses \>400 international units daily
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemoglobin A1c | 3 months |
Countries
United States
Outcome results
None listed