Effectiveness of TheraNeem Lip Therapy for Herpes Simplex Labialis

Effectiveness of TheraNeem Lip Therapy of Common Symptoms of Herpes Simplex Labialis A Prospective Experimental Case Series (n=5)

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00985335

Acronym

Neem

Enrollment

Registered

2009-09-28

Start date

2009-08-31

Completion date

2011-03-31

Last updated

2011-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Herpes Simplex

Brief summary

This study intends to test the efficacy of the TheraNeem Lip Therapy balm for Herpes Simplex. The study will include a total of 5 people.

Detailed description

Qualified candidates will be officially enrolled into the study within 24 hours of their subsequent outbreak of Herpes Simplex Labialis. They will be given all of the Neem Therapy products to use, and photographs and questionnaires will be taken to assess their progress.

Interventions

OTHERNeem Based External Application Cream

Apply externally 3-4 times per day

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

1. Participant has signs and symptoms of HSV-1 infection of less than 24 hours duration to the Southern California University of Health Sciences investigators 2. Participants ages 18-70 years 3. Confirmation of oral-circumoral herpes lesion will be made by a clinician in the presence of oral-circumoral lesion assumed to be HSV-1 for purposes of study 4. Subjects expressed willingness to comply with protocol 5. Subject will be willing to have the presenting lesion photographed twice 6. Subject sign a written informed consent, HIPPA disclosure, Experimental bill of rights

Exclusion criteria

1. History of past or present immunosuppressive condition, or currently taking immunosuppressive medication 2. History of adverse effects or allergies to any Neem based product or containing any of the other ingredients TheraNeem Lip Therapy: Organic Coconut Oil, Organic Beeswax, Organic Jojoba Oil, Shea Butter, Sesame Oil, Organic Neem Oil, , Essential Oil of Peppermint, Vitamin E (Tocopherol) 3. Signs of disseminated HSV illness 4. History of use of oral or topical antiviral agents within 10 days of screening and/or at start of study visit 5. Pregnancy or lactation 6. Psychiatric disorder 7. Inability to understand or follow the instructions

Design outcomes

Primary

Measure	Time frame
Cold Sore Symptom Scale	Baseline and End of Treatment

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026