Glioma, Meningioma
Conditions
Keywords
glioma, meningioma, VEGF
Brief summary
Objectives: This study is looking at the level of vascular endothelial growth factor (VEGF) circulating in the blood stream of patients diagnosed with either a meningioma or a glioma. The questions that will be addressed include: 1. Can VEGF level alert us to tumor progression or recurrence before MRI changes occur? 2. Is the VEGF level an indicator of the response to treatment? 3. Does the VEGF level correlate with tumor histology and behavior? 4. Is there a relationship between VEGF level and outcome?
Interventions
PROCEDUREBlood test
an additional vial of blood will be obtained at the time of MRI or at the time of routine blood tests ordered by the medical oncologist. In other words, there will be no extra needle sticks. Just an extra vial of blood will be taken during a routine blood test
Sponsors
Upper Michigan Brain Tumor Center
Marquette General Health System
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* any patient presenting with glioma or meningioma
Exclusion criteria
* a different type of brain tumor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Determine if VEGF levels correlate with tumor progression or recurrence | every one to three months |
Secondary
| Measure | Time frame |
|---|---|
| Determine if the VEGF level is an indicator of the response to treatment. | Every one to three months |
| Determine if the VEGF level correlates with tumor histology and behavior. | Every one to three months |
| Determine if there is a relationship between VEGF level and outcome. | Every one to three months |
Countries
United States
Outcome results
None listed