Gene - Exercise Research Study

Impact of Common Genetic Polymorphisms on CV Disease Risk Factor Changes With Endurance Exercise Training

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00976742

Acronym

GERS

Enrollment

225

Registered

2009-09-14

Start date

1998-06-30

Completion date

Unknown

Last updated

2025-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Disease Risk Factors

Keywords

plasma lipoprotein lipids, body composition, glucose tolerance, inflammation markers, insulin sensitivity, coagulation markers

Brief summary

The investigators hypothesize that the degree to which older generally healthy but sedentary men and women improve a number of cardiovascular (CV) disease risk factors with 6 months of highly-standardized endurance exercise training will be a function of common genetic variations in candidate genes.

Interventions

BEHAVIORALEndurance exercise training

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

PREVENTION

Eligibility

Sex/Gender

ALL

Age

50 Years to 75 Years

Healthy volunteers

Inclusion criteria

* generally healthy * free from CV disease * ability to undergo exercise training

Exclusion criteria

* previous history of CV disease

Design outcomes

Primary

Measure	Time frame
Cardiovascular Disease Risk Factors	~9 months

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026