Psychophysiological Correlates of Mindfulness Based Cognitive Therapy (MBCT) in Recurrent Depression

Psychophysiological Correlates of Mindfulness and Attention in Recurrent Depression and Healthy Volunteers

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00974077

Acronym

MBCT & EEG

Enrollment

120

Registered

2009-09-10

Start date

2008-09-30

Completion date

2011-07-31

Last updated

2014-12-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Keywords

recurrent depression,, mindfulness training, attention, Evoked EEG potentials, Relapse prevention in recurrent depression

Brief summary

The study investigates cognitive attention, rumination and psychophysiological (EEG) processes in healthy subjects and remitted patients with at least three previous depressive episodes. The investigators expect that Mindfulness Based Cognitive Therapy prevents future depressive episodes and has influence on cognitive and psychophysiological measures.

Interventions

BEHAVIORALMindfulness Based Cognitive Therapy

Group treatment over 8 weeks with training in meditation, stress regulation, shift attention, stay present, in addition with cognitive and behavioral strategies (following Williams et al. Manual 2002)

OTHERWaiting List Control

Patients receive MBCT with a delay of 6 months.

Study design

Allocation

RANDOMIZED

Intervention model

FACTORIAL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* recurrent depression with at least 3 previous MD-episodes, currently remitted (no symptoms)

Exclusion criteria

* current depression * lifetime schizophrenia * bipolar or schizoaffective disorder * any neurological disorders * other psychopathology during last 3 years

Design outcomes

Primary

Measure	Time frame
Relapse (MDE)	12 month

Secondary

Measure	Time frame
Electroencephalography (EEG)	6 month

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026