The Swiss Venous Thromboembolism Cohort 65+

Conditions

Venous Thromboembolism

Brief summary

The purpose of this prospective multicenter cohort study is to examine long-term medical outcomes, quality of life, and medical resource utilization in elderly patients (\>= 65 years) with acute venous thromboembolism (i.e., acute pulmonary embolism and/or deep vein thrombosis)

Jaquet E, Tritschler T, Stalder O, Limacher A, Méan M, Rodondi N, Aujesky D.

2018-05-3011 citations

10.1111/jth.14137

Derivation and validation of a novel bleeding risk score for elderly patients with venous thromboembolism on extended anticoagulation

Andreas Limacher, Marie Méan, Jürg H. Beer, Joseph Österwalder, Beat Frauchiger et al. (16 authors)

Thrombosis and Haemostasis2017-01-0125 citations

10.1160/th17-03-0162

Echocardiography does not predict mortality in hemodynamically stable elderly patients with acute pulmonary embolism.

Hofmann E, Limacher A, Méan M, Kucher N, Righini M, Frauchiger B, Beer JH, Osterwalder J, Aschwanden M, Matter CM, Banyai M, Egloff M, Hugli O, Staub D, Bounameaux H, Rodondi N, Aujesky D.

2016-07-2710 citations

10.1016/j.thromres.2016.07.014

Comparison of Cardiac and Non-Cardiac Biomarkers for Risk Stratification in Elderly Patients with Non-Massive Pulmonary Embolism

Nicolas Vuilleumier, Aurélien Simona, Marie Méan, Andreas Limacher, Pierre Lescuyer et al. (9 authors)

PLoS ONE2016-05-2425 citations

10.1371/journal.pone.0155973

Predicting recurrence after unprovoked venous thromboembolism: prospective validation of the updated Vienna Prediction Model

Tobias Tritschler, Marie Méan, Andreas Limacher, Nicolas Rodondi, Drahomir Aujesky

Blood2015-09-0445 citations

10.1182/blood-2015-04-641225

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

No

Inclusion criteria

* Objectively confirmed acute pulmonary embolism and/or deep vein thrombosis * Age \>=65 years

Exclusion criteria

* Thrombosis at a different site than lower limb * Catheter-related thrombosis * Insufficient spoken language ability in German or French * Follow-up not possible (e.g., terminally ill patients) * Informed consent not possible (e.g., severe dementia) * Prior enrolment in the study

Design outcomes

Primary

Measure	Time frame
Venous thromboembolism recurrence	3-48 months

Secondary

Measure	Time frame
Overall mortality	3-48 months
Major bleeding	3-48 months
Post-thrombotic syndrome	3-48 months
Generic and disease-specific health-related quality of life	3-48 months
Medical resource utilization	3-48 months

Countries

Switzerland

Outcome results