Retinal Function in Relation to Long Term Changes in the Glucose Level

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00973401

Enrollment

Registered

2009-09-09

Start date

2009-09-30

Completion date

2010-06-30

Last updated

2009-09-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes Mellitus

Brief summary

The purpose of this study is to measure the amplitude and implicit time of electroretinogram (ERG), darkadaptation and the calibre of retinal vessels before and after optimized medical treatment of diabetic individuals (a lower blood glucose level) over a period of 12 months. Newly diagnosed type 1 and type 2 diabetics as well as dysregulated type 1 and type 2 diabetic individuals will be included. Retinal vessel calibre measurements will be used as an estimation of changes in the retinal perfusion.

Interventions

OTHERInsulin pump

Patients receive an insulin pump that optimizes their glucose control.

Study design

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

* Dysregulated type 1 diabetic individuals and newly diagnosed type 1 diabetics. Age \>17 \< 60 years

Exclusion criteria

* Test individuals with significant cataract, prior surgery to the eye, diabetic retinopathy, other serious eye disease, hypertension, other serious systemic disease.

Design outcomes

Primary

Measure	Time frame
Changes in amplitude/implicit times, retinal vessel diameter, dark adaptation and OCT	1 week, 1 month, 4 months, 1 year

Countries

Denmark

Contacts

Primary ContactStig Holfort, medical doctor

+4543234817

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026