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The Effects of Pistacia Mutica on De Novo Dental Plaque Formation, Gingival Inflammation and Oral Microorganisms

The Effects of Pistacia Mutica on De Novo Dental Plaque Formation, Gingival Inflammation and Oral Microorganisms

Status
Completed
Phases
Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00972803
Enrollment
25
Registered
2009-09-09
Start date
2008-05-31
Completion date
2009-05-31
Last updated
2009-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingivitis

Keywords

gingivitis, dental plaque, mouthrinse

Brief summary

Dental plaque is a well known etiologic factor for gingivitis. Recently, herbal extracts are a matter of scientific interest to inhibit plaque accumulation on teeth. The purpose of this study was to evaluate the effects of pistacia Mutica (PM) mouth wash on de novo dental plaque plaque formation, gingival inflammation indices and oral microorganisms.

Interventions

DRUGpistacia Mutica extract

The subjects were asked to use a mouthwash containing pistacia Mutica extract twice a day for 4 days.

DRUGPlacebo

The subjects were asked to use a placebo mouthwash twice a day for 4 days.

DRUGChlorhexidine

The subjects were asked to use a mouthwash containing Chlorhexidine twice a day for 4 days.

Sponsors

Tabriz University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years

Inclusion criteria

* had merely gingivitis (pocket depth≤3 mm, no attachment loss) * without any fixed or removable oral appliances

Exclusion criteria

* Individuals who had a history of any relevant systemic diseases * Individuals who had a history of any drug usage

Design outcomes

Primary

MeasureTime frame
The effects of pistacia Mutica extract (PM) on de novo plaque formation.In a 4 days experimental periods followed by a 10 days wash-out periods.

Secondary

MeasureTime frame
staining effects of pistacia Mutica extract in comparison to placebo or ChlorhexidineIn a 4 days experimental periods followed by a 10 days wash-out periods

Countries

Iran

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026